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《International Journal of Laboratory Medicine》 2013-24
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The metabolic characteristics of lipid profile and homocysteine in the patients with subclinical hypothyroidism

Wei Yan;Xie Jiamei;Shi Lixin;Jiangdu People′s Hospital;  
Objective To study metabolic characteristics of lipid profile and homocysteine in the patients with subclinical hypothyroidism(SCH).Methods 92patients with SCH,34patients with hypothyroidism and 57control subjects were recruited in the study.Serum HS-TSH,TC,TG,LDL-C,HDL-C and HCY were measured and compared.Results The levels of TC,LDL-C and HCY were higher in patients with SCH than the control subjects(P0.01).The levels of TC,LDL-C and HCY had significant differences between patients with SCH and patients with hypothyroidism(P0.05).After treatment,The levels of TSH,TC,HCY and LDL-C were significantly decreased,except TG and HDL-C.HS-TSH was positively correlated with TC,LDL-C and HCY.Conclusion SCH was a risk factor of abnormal lipid metabolism and hyperhomocystinemia.
【CateGory Index】: R581.2
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