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Application and advance of apoptosis ~(99m)Tc labelled annexin V imaging in tumor research

ZHANG Xin, LI Ya-ming (Department of Nuclear Medicine, The First Hospital Affiliated to Dalian Medical University, Dalian 116011, China; Department of Nuclear Medicine, The First Hospital Affiliated to China Medical University, Shenyang 110001, China)  
Apoptosis plays an important role in tumor processes. Successful therapy induces apoptosis of neoplastic cells in tumor tissue. Apoptosis 99mTc labelled annexin V imaging enables non-invasive in vivo detect treatment-induced apoptosis on the early stage. It will be useful in early assessment the efficacy of cancer therapies and disease prognosis in individual patients.
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