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《Drugs & Clinic》 2010-01
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Recent advances in the study on antitumor effects of flavonoids

ZHU Rong-xin1,2,ZHANG Sai-long1,2,JIN Yong-sheng2(1.Department of Postgraduates Administration,Second Military Medical University,Shanghai 200433,China;2.School of Pharmacy,Second Military Medical University,Shanghai 200433,China)  
Flavonoids are commonly polyphenolic compounds in plant with extensive pharmacological activities.Recent studies showed that nature and artificially synthesized flavonoids could exhibit significant antitumor activities,and the combination treatment with some active flavones could change the antitumor effects.Some nature flavonoids and chalcone derivates can reverse the multi-drug resistance of tumor cell.This review summarize recent studies on the mechanism of antitumor effects,multi-drug resistance reverse and structure-activity relationships of the flavonoids.
【CateGory Index】: R285.5
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