Clinical observation of Shenkang Suppository combined with Shenshuaining Tablets in treatment of chronic renal failure
CHEN Li;Department of Nephrology, Traditional Chinese Medicine Hospital of Yongchuan District in Chongqing;
Objective To explore the clinical effect of Shenkang Suppository combined with Shenshuaining Tablets in treatment of chronic renal failure. Methods Patients(64 cases) with chronic renal failure in Traditional Chinese Medicine Hospital of Yongchuan District in Chongqing from March 2013 to February 2015 were randomly divided into control and treatment groups, and each group had 32 cases. The patients in the control group were po administered with Shenshuaining Tablets on the basis of routine therapy, 5 tablets/time, three times daily. The patients in the treatment group were given Shenkang Suppository by rectum on the basis of control group, 5 grains/d, early, middle and late each 1 grain, and the remaining 2 grains were used before sleeping. The patients in two groups were treated for 45 d. After treatment, the clinical efficacy were evaluated, and the changes of BUN, Scr, Ccr, and 24 h Upm before and after treatment in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 62.5% and 75.0%, respectively, and there were differences between two groups(P 0.05). After treatment, BUN, Scr and 24 h Upm in two groups were significantly decreased, Ccr was significantly increased, and the difference was statistically significant in the same group(P 0.05). After treatment, the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups(P 0.05). The adverse reactions incidences in control and treatment groups were 9.36% and 6.25%, and there was no statistical significance between the two groups. Conclusion Shenkang Suppository combined with Shenshuaining Tablets has clinical curative effect in treatment of chronic renal failure, and can improve indicators related renal function with a lower incidence of adverse reactions, which has a certain clinical application value.
【CateGory Index】： R692.5