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《Journal of Guangxi Medical University》 2001-06
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Wei Changyuan,Li Ting,Tang Zongping,et al (Affiliated Cancer Hospital, Guangxi Medical University,Nanning,530021 China)  
Objective:To study the apoptosis induced by KLT in human hepatocellular carcinoma Methods:MTT,immunohistochemical and electronic microscopic methods were used in 34 cases to observe primary liver cancer treated with KLT in vitro,compared to the control group Results:① KLT can inhibit hepatocellular carcinoma cell proliferation up to 30% ② Comparing to the control group, hepatocellular carcinoma cells treated with KLT showed significant apoptosis and p53 expression(P0 05) ③ under the electronic microscope,the characteristics of apoptosis,such as the formation of cell membrane blebs and apoptotic bodies were observed in hepatocellular carcinoma cells Conclusion:KLT can induce apoptosis in hepatocellular carcinoma cells It may increase the p53 gene expression
【Fund】: 广西区卫生厅课题 ( z982 8)
【CateGory Index】: R735.7
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