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《ACTA ACADEMIAE MEDICINAE GUANGXI》 1994-01
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THE RELATONSHIP BETWEEN DNA CONTENT AND IMMUNOMAHISTOCHEMICAL CHANGES OF LIVER CELL DYSPLASIA

Feng Zhenbo; Li Zhishang;Luo Dianzhong; et al(Department of Pathology)  
The expressions of γ-glutamyl transpeptidases(γ-GT),alphafetaprotein (AFP)and carcinoemybryonic antigen(CEA) were studied histochemically in 22 cases of liver celldysplasia(LCD).The nuclear DNA content of the cells wasmeasured by OPTON Ⅲmicrospectrophotometry in 17 cases of LCD, The results showed that the three tumor markersin LCD were neither like those in HCC nor like thosein non-dysplastic liver cells. The meanDNA content and the distribution of the euploids of LCD lay between those of HCC and nonliver cell dysplasia(P 0.05~0.01)These results suggest that LCD is a group of proliferatingcells,and those with rehtively high ratio ofaneuploid cells might be premalignant.
【Fund】: 国家自然基金
【CateGory Index】: R735.7
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