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PREPARATION OF AN ALLERGIC INFLAM-MATORY AIRWAY MODEL

Shi Huanzhong;Chen Yiqiang;Xu Hui,et al(First Affiliated Hospital,Guangxi Medical U niversity Nanning 530021)  
This study described the changes of the eosinophil(EOS)counts in the bronchoalveo-lar lavage fluid(BALF)obtained from ovalbumin(OVA)-sensitized BALB/C mice.It was foundthat there was a severe eosinophilia in BALF(9. 76±0.80)×108/Lafter the mice were sensitizedwith 3 intraperitoneal injections of OVA(10μg per animal),and were then challenged with anaerosol of 5%OVA for 20 min, once a day for 6 days.This method produces an ideal allergic in- flammatory airway model.
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