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A bioinformatics analysis on 3-hydroxy-3-methylglutaryle-CoA reductase, a key enzyme in plant isoprenoid biosynthesis

LI Rong, WANG Zhe-zhi ( College of Life Sciences, Shaanxi Normal University, Xi’an 710062, China )  
In the present study,3-hydroxy-3-methylglutaryl-CoA reductase from rubber,tobacco,capsicum and andrographis,which were registered in GenBank,were analyzed and predicted by the tools of bioinformatics in the following aspects:the composition of nuclei acid sequences and amino acid sequences,signal peptide,transmembrane topological structure,hydrophobicity or hydrophilicity,secondary and tertiary structure of protein, molecular phylogenetic evolution and so on. The results are as follows:the full-length gene of HMGR contains an opening reading frame,5′-untranstrated region and 3′-untranstrated region;HMGR is a hydrophilic and transmembrane protein which lack of signal peptide;the amino acid sequences of HMGR include two functional HMG-CoA binding motifs and two functional NADPH binding motifs;the main motif of predicted secondary structure of HMGR are alpha helix and random coil,beta turn and extended strand are spreaded in the whole secondary structure of protein;the predicted tertiary structure of functional domain of HMGR includes the helical N-domain,S-domain and L-domain.
【Fund】: 国家“十五”科技攻关项目(2004BA721A35)~~
【CateGory Index】: Q946
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2 FAN Jing,XU Cheng-hao,ZHANG Xi-yu,LIU Chao,HUANG Ming-yuan (College of Chemistry and Life Science, Leshan Normal University, Leshan 614004, Sichuan, China);Bioinformatics Analysis of LeNHX3 Gene in Tomato[J];Hubei Agricultural Sciences;2009-12
3 WANG Qiu-jun*2,WANG Jian-wen*3 School of Pharmaceutical Sciences,Soochow University,Suzhou Jiangsu 215123,China;Recent Research Advances on Antimicrobial Activities and Biosynthesis of Phytosteroids[J];Anti-Infection Pharmacy;2012-02
4 QIU Xi-Er;ZHU Dong-Fa;CUI Xiao-Yu;TANG Jie;XIE Xi;School of Marine Science, Ningbo University;;CLONING AND EXPRESSION OF HMGR GENE IN PORTUNUS TRITUBERCULATUS DURING MOLTING[J];Oceanologia et Limnologia Sinica;2014-06
5 Dong Lemeng Liu Yujun (Beijing Forestry University,Beijing 100083) Wei Jianhe (Institute of Medicinal Plant Development,Chinese Academy of Medicinal Sciences,Chinese Peking Union Medical College,Beijing,100193);Cloning of Critical Gene Fragments in Saikosaponin Biosynthesis and Associated Sequence Analysis[J];World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica;2008-05
6 YANG He GAO Yu-gang LI Fan-ying ZHANG Lian-xue(Jilin Agriculture University College of Chinese Traditional Medicine,Changchun 130118,China);Research Progress on Biosynthetic Pathway of Terpenoids Containing Ginsenoside and the HMGR[J];China Biotechnology;2008-10
7 Fan Jing Dai Juan Hu Jianping Liang Zi Huang Mingyuan(College of Chemistry and Life Science,Leshan Normal University,Leshan 614004);Bioinformatics Research on the Tomato LeNHX1 Gene[J];Biotechnology Bulletin;2009-12
8 JI Yan-yun,HUA Wen-ping,WANG Zhe-zhi(Key Laboratory of Ministry of Education for Medicinal Plant Resource and Natural Pharmaceutical Chemistry,National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China,Shaanxi Normal University,Xi′an 710062,Shaanxi,China);Cloning and bioinformatics analysis of Cu/Zn-SOD gene from Salvia miltiorrhiza Bunge[J];Journal of Shaanxi Normal University(Natural Science Edition);2011-03
9 YANG Jin-fen1,2,HE Guo-zhen2,3,Megha Nath Adhikari2,3,XU Hui1,2,HE Rui1,2,ZHAN Ruo-ting1,2,CHEN Wei-wen1,2(1.Research Center of Chinese Herbal Resource Science and Engineering,Guangzhou University of Chinese Medicine,Guangzhou,510006,China;2.Key Laboratory of Chinese Medicine Resources of Ministry of Education,Guangzhou,510006,China;3.College of Chinese Medicine,Guangzhou University of Chinese Medicine,Guangzhou,510006,China);Clone and Analysis of Gene Encoding 3-hydroxy-3-methylglutaryl Coenzyme A Reductase from Amomum villosum[J];Lishizhen Medicine and Materia Medica Research;2010-08
10 LIN Rongyan;LAI Zhongxiong;Institute of Horticultural Biotechnology,Fujian Agriculture and Forestry University;;Cloning and qPCR Analysis of HMGR Gene from Dendrobium huoshanense[J];Chinese Journal of Tropical Crops;2014-10
Chinese Journal Full-text Database 1 Hits
1 CHEN Da_Hua, YE He_Chun *, LI Guo_Feng, LIU Yan (Institute of Botany, The Chinese Academy of Sciences, Beijing 100093, China);Advances in Molecular Biology of Plant Isoprenoid Metabolic Pathway[J];ACTA BOTANICA SINICA;2000-06
Chinese Journal Full-text Database 10 Hits
1 He Zhijun, Wang Xu\= Department of Life Sciences, Yunnan Normal University, Kunming\ 650092 \=\=;STUDY OF MITOTIC EFFECTS OF ATROPINE IN V\-\{79\} CHINESE HAMSTER CELLS[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1999-03
2 XU Zhong-dong 2 PENG Jing-zhong( 1 Anhui Institute of Education ,Hefei,230061, 2 Anhui Yuexi Peace Middle School,Yuexi,246600);Mitochondria and Apoptosis[J];Journal of Anhui Institute of Education;2001-06
3 YU Xiao-liang,WANG Jian-hua(College of Agronomy,Shandong Agricultural University,Taian 271018,China);Determination of Effective Components in Chaenomeles Fruits[J];Shandong Agricultural Sciences;2012-02
4 Yu Junhong1 Huang Mianjia2 Tian Weimin1 (1 Key Laboratory of Agriculture Ministry for the Cultivation and Physiology of Tropical Crops,Rubber Research Institute,Chinese Academy of Tropical Agricultural Sciences,Danzhou,Hainan 571737;2 College of Horticulture,South China University of Tropical Agriculture,Danzhou,Hainan 571737);Progress on the Regulation of Natural Rubber Biosynthesis in Hevea Brasiliensis[J];Anhui Agricultural Science Bulletin;2007-12
5 Yuan Lu et al.(School of Life Science,Southwest University;Key Laboratory of Eco-Environments in Three Gorges Reservoir Region(Ministry of Education);Key Laboratory of Aquatic Science of Chongqing;Chongqing 400715);Apoptosis Induction of Blood Cells in Aristichthys nobilis by Cu~(2+) Stress[J];Anhui Agricultural Science Bulletin;2009-03
6 Hou Lixia et al.(Department of Life Science,Qingdao Agricultural university,Qingdao 266109,China);Exploration about Teaching of Introduction in Cell Biology[J];Anhui Agricultural Science Bulletin;2011-17
7 SUN Hai-yan et al (Changshu Institute of Technology, Changshu, Jiangsu 215500);Study on Secondary Metabolism Genetic Engineering about Insect Resistance[J];Journal of Anhui Agricultural Sciences;2005-10
8 ZHU Dao-wei et al(College of Forestry and Horticulture,Henan Agricultural University,Zhengzhou,Henan 450002);Application of the Flow Cytometry in the Identification of Fruit Ploidy[J];Journal of Anhui Agricultural Sciences;2006-24
9 CHEN He et al(College of Life Science and Engineering,Shaanxi University of Science and Technology,Xi'an,Shaanxi 710021);Study on Technical Conditions for Degrading Corn Stalk by Compound Enzyme[J];Journal of Anhui Agricultural Sciences;2007-29
10 CAI Ping et al(Xilinguole Vocational College,Xilinghaote,Inner Mongolia 026000);Observation of the Pollen Morphology of 5 Species of Caragana Fabr Plants in Alashan Desert[J];Journal of Anhui Agricultural Sciences;2007-33
China Proceedings of conference Full-text Database 10 Hits
1 Lü Jin-yin LU Li GAO Jun-feng (College of Life Science, Northwest Sci-Tech University of Agriculture and Forestry, Yangling, Shaanxi 712100,,China);Effect of Different Dose ~(60)Co Radiation on Activity of Protective Enzyme in Wheat Leaves[A];[C];2005
2 LIU Wen-juan XING Da-zhou LU Ying-min (College of Landscape Architecture,Beijing Forestry University,China National Engineering Research Center for Floriculture,Beijing 100083);Studies on Different Pollination Methods of Hybridization among Lily Cultivars[A];[C];2007
3 SUN Chong-bo~(1,2) XIANG Lin~1 SHI Ji-sen~2 GUO Fang-qi~1 LI Bo-jun~1 QIN De-hui~1 (1 Institute of Horticulture,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021;2 Key Laboratory of Forest Tree Genetics and Gene Engineering of State Forestry Administration,Nanjing Forestry University,Nanjing 210037);Scanning Electron Microscope Observation on Pollinium Morphology in 5 Genus 11 Species of Orchidaceae[A];[C];2010
4 PENG Yi-sheng~(1,3) ZHUANG Xue-ying~1 HE Yi-xiong~2 HUANG Jiu-xiang~1 PAN Li-jun~1 KE Huang~1 (1 College of Forestry, South China Agri. Univ., Guangdong, Guangzhou 510642, China) (2 Zhuhai Wildlife Protection and Administration Institute, Guangdong, Zhuhai 510900, China) (3 School of Environmental Science and Engineering, Sun Yat-sen University, Guangdong, Guangzhou, 510275, China);A Study on Spermatophytic Flora and Feeding Plant Resources of Rhesus Monkey on Dan'gan Island Nature Reserve[A];[C];2007
5 PENG Yi-sheng~(1,3) ZHUANG Xue-ying~1 HE Yi-xiong~2 HUANG Jiu-xiang~1 PAN Li-jun~1 KE Huang~1 (1 College of Forestry,South China Agri.Univ.,Guangdong,Guangzhou 510642,China) (2 Zhuhai Wildlife Protection and Administration Institute,Guangdong,Zhuhai 510900,China) (3 School of Environmental Science and Engineering Sun Yat-sen University,Guangdong,Guangzhou,510275,China);A Study on Spermatophytic Flora and Feeding Plant Resources of Rhesus Monkey on Dan'gan Island Nature Reserve[A];[C];2007
6 YANG Xiao-zhen~1 WU Xu-gan~1 YAO Gui-gui~1 CHENG Yong-xu~1 WANG Chun-lin~2 (1.Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources,Shanghai Fisheries University,Shanghai 200090,China; 2.College of Life Science and Biotechnology,Ningbo University,Ningbo 315211,China);Ultrastructure of Oocytes and Follicular Cells of Portunus trituberculatus during the First Reproductive Cycle[A];[C];2008
7 MA Yongjie~1 XU Kaili~2 GU Hongchen~1 (1.National Key Laboratory of Nano/Micro Fabrication Technology,Key laboratory for thin film and microfabrication of Ministry of Education,Institute of Micro and Nano science and technology,Shanghai Jiaotong University,Shanghai 200030; 2.Cancer Institute of Shanghai Jiaotong University and Shanghai Cancer Institute,Shanghai 200032);Study on endocytosis of aminosilane-coated magnetite nanoparticles by human lung adenocarcinoma cells SPC-A-1 and Normal human lung embryo cells WI-38 in vitro[A];[C];2005
8 CHEN Xi, WANG Shi-yu (College of Landscape and Horticultural, Yunnan Agricultural University, Yunnan Kunming 650201,China);The resources research and to exploit using of Chinese bramble (Rubus L.)[A];[C];2006
9 PAN Jing-zhi,XU Yan-duo,WANG Qi (College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun,Jilin 130118,China);Isolation,Identification and Chemical Composition Preliminary Study on Endophytic Fungi from Polygonatum odoratum[A];[C];2007
10 ZHANG Yin-hua,LI Qiu-ming,SUN Ying-jian (Department of Veterinary Medicine and Animal Science,Beijing Agriculture College,Beijing,102206,China);Effect of Eprinomycin on Cell Proliferation on N2a Cells[A];[C];2010
Chinese Journal Full-text Database 10 Hits
1 ZHU Jing-tong,FAN Yu-ling,LU Xin-hua,DONG Yue-sheng,ZHENG Zhi-hui,ZHANG Hua,HE Jian-gong(New Drug Research & Development Center of North China Pharmaceutical Group Corporation,National Microbial Medicine Engineering & Research Center,Shijiazhuang 050015,China);In Vitro Anti-tumor Effect of Ophiobollin from Microorganism[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-05
2 ZHENG Ling1,2,HUO Xue-han1,2,WANG Fu-rong2,ZHANG Jun1,2(1.College of Life Science,Shandong Normal University,Jinan 250014,China; 2.Shandong Subcenter of National Cotton Improvement Center of China/Shandong Cotton Research Center,Jinan 250100,China);Bioinformatic Analysis on Two GhBI-1 Genes of Upland Cotton[J];Shandong Agricultural Sciences;2011-03
3 XU Guang-tao(Anhui Forestry High-Tech Development Center,Hefei 230032,China);Study on Methods of Improving the Survival Rate of Bionic Cultivation of Dendrobium huoshanense[J];Anhui Forestry Science and Technology;2011-06
4 Ma Jiyi etal.(Qinghai Normal University college of life science and Geography,xining 810008,China);Advances in Studies on Bulbus Fritillaria uni-bracteata Hsiao et K.C.Hsia.[J];Anhui Agricultural Science Bulletin;2010-15
5 Fu Yulan et al (Anhui Agricultural University, Hefei, Anhui 230036);Research on the Tissue Culture and Rapid Propagation of Dendrobium Huoshanense[J];Journal of Anhui Agricultural Sciences;2004-03
6 Pu Gaobin et al (Horticultural College of Shandong Agricultural University,Taian,Shandong 271018);Effect of Light Quality on the Growth and Antioxidant Enzyme Activities of Tomato Seedlings[J];Journal of Anhui Agricultural Sciences;2004-05
7 ZHOU Guo-li et al(College of Life Science,Liaocheng University,Liaocheng,Shandong 252059);Research Advance in Candidate Gene Affecting Pig Meat Quality Trait[J];Journal of Anhui Agricultural Sciences;2006-04
8 ZHENG Ya-qin (College of Agro-forestry Sciences,Linyi Normal University,Linyi,Shandong 276003);Study on Cymbidium hyhridum Culture in Vitro and Plant Regeneration[J];Journal of Anhui Agricultural Sciences;2006-12
9 QUAN Xian-qing et al (High-Technology Research Center,Shandong Academy of Agricultural Sciences/Key Laboratory for Genetic Improvement of Crop and Poultry of Shandong Province,Jinan,Shandong 250100);Metabolism and its Regulation Mechanism of Abscisic Acid in Higher Plants[J];Journal of Anhui Agricultural Sciences;2006-13
10 ZHANG Dong-mei et al (Shanghai Landscape Gardening Research Institute,Shanghai 200232);Study on the Extraction of Anthocyanin of Acer platanoides and its Stability[J];Journal of Anhui Agricultural Sciences;2006-13
China Proceedings of conference Full-text Database 2 Hits
1 Fu Naiguang,Lin Zhaohua,Tian Qing ,Liang Zhenyi ,Chen Yiping;Primary Studies on the Distillation Equipments of the Eucalyptus essential oil[A];[C];2008
2 HAN Bao-yu, ZHOU Peng, ZHANG Jin-ming ( Key Laboratory of Tea Chemical Engineering of Ministry of Agriculture, P. R. China, Tea Research Institute of Chinese Academy of Agricultural Sciences, Hangzhou 310008, China );Releases of MeSA and E-2-hexenal from Tea Shoots Induced by Pests' Damaging and Exotic MeSA and Attraction Impact of Both Synomones on Natural Enemies in Tea Gardens[A];[C];2006
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 FU Yue-wei et al(College of Horticulture,Jilin Agricultural University,Changchun,Jilin 130118);Effects of Water Stress on Photosynthesis Character of L. fischeri[J];Journal of Anhui Agricultural Sciences;2010-03
2 GUO Chun-lan,ZHANG Lu(College of Landscape and Art,Jiangxi Agricultural University,Nanchang 330045,China);Cloning and sequence analysis of SOD gene of Camellia oleifera[J];Pratacultural Science;2012-03
3 JIANG Jun-fu,LI Xiong-ying,WU Yao-sheng,LUO Yu,ZHOU Juan,ZHAO Rui-qiang(Department of Biochemistry and Molecular Biology,Guangxi Medical University,Nanning 530021,China);Cloning and Sequence Analysis of Squalene Epoxidase Gene from Gynostemma pentaphyllum[J];Acta Botanica Boreali-Occidentalia Sinica;2010-08
4 Xing Zhaobin,Long Yuehong,Li Baocai,He Shan,Liang Nengsong,Zhu Jinli(Hebei United University,Tangshan 063000,P.R.China);Copper/Zinc Superoxide Dismutase Gene Cloning in Eleutherococcus senticosus and Its Expression by Endophytic Fungus[J];Journal of Northeast Forestry University;2013-01
5 YE Yao-hui;HE Jin;YING Ya-bin;Jiangxi University of Traditional Chinese Medicine;The Family Planning Service Center of Jizhou District;;Advances on the method of extraction and purification of Alkaloids in Fritillaria[J];Journal of Gannan Medical University;2013-04
6 YAN Xiao-fei;HUANG Bing;HAN Hong-yu;YANG Bin;YUE Cheng;ZHAO Qi-ping;JIANG Lian-lian;DONG Hui;Science and Technology Department,Xinjiang Agricultural University;Key Laboratory for Animal Parasitology of Ministry of Agriculture,Shanghai Veterinary Research Institute,Chinese Academy of Agricultural Sciences;College of Animal Medicine,Xinjiang Agricultural University;;Cloning and Bioinformatics Analysis of cDNA Expression Libraries in Eimeriaacervulina[J];China Animal Husbandry & Veterinary Medicine;2014-07
7 PING An1,YANG Guo-ting1,GAO Fang2,WEI Jin-ling3 (1. Northeast Forestry University,Harbin 150040,China; 2. Dailing Forestry Research Institute, Yichun 153106,China; 3 Heilongjiang Forestry Engineering and Environment Institute,Harbin 150081,China);Effect of Pyroligneous Acid Sprinkled on Leaves to the Yield of Panax Ginseng and Content of Ginsenoside[J];Acta Agriculturae Boreali-Sinica;2010-04
8 JIANG Shi-cui1,ZHANG Ming-zhe1,WANG Yi1,SUN Chun-yu1,LI Xiao-kun1,2,ZHANG Mei-ping1(1.College of Life Science,Jilin Agricultural University,Changchun 130118,China;2.Engineering Research Center of Bioreactor and Pharmaceutical Development of Ministry of Education,Jilin Agricultural University,Changchun 130118,China);Interference Vector Construction of Panax ginseng's SQS Gene and Transformation Callus[J];Journal of Jilin University(Science Edition);2011-06
9 WU Bo1,GAO Dan2,PAN Chao-mei3,LUO Guang-ming2,ZHANG Shou-wen2(1.Chinese Medicine Germplasm Resource Engineering Technology Research Center,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;2.College of Medicine,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;3.College of Pharmacy,Guangzhou University of Chinese Medicine,Guangzhou 510006,China);Cloning of SOD Gene Segments and SNP Analysis in Evodia rutaecarpa[J];Acta Agriculturae Universitatis Jiangxiensis;2011-06
10 XING Zhao-bin,WU Peng,LONG Yue-hong,HE Shan,XIU Le-shan(College of Biology,Hebei United University,Tangshan 063000,China);Cloning and expression analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Eleutherococcus senticosus[J];Jiangsu Journal of Agricultural Sciences;2012-06
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Cai Guoqin Li Guozhen (Biology Department,Beijing Normal University,Beijing 1000088) Ye Hechun Li Guofeng (Institute of Botany, Academia Sinica, Beijing 100044);Hairy Root Culture of Artemisia annua L. by Ri Plasmid Transformation and Biosynthesis of Artemisinin[J];Chinese Journal of Biotechnology;1995-04
2 1LIU Chang Jun 1MENG Yu Ling 2HOU Song Sheng 1CHEN Xiao Ya ** (National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology, The Chinese Academy of Sciences, Shanghai 200032) (Wuhan Inst;CLONING AND SEQUENCING OF A cDNA ENCODING FARNE SYL PYROPHOSPHATE SYNTHASE FROM GOSSYPIUM ARBOREUM AND ITS EXPRESSION PATTERN IN THE DEVELOPING SEEDS OF GOSSYPIUM HIRSUTUM cv. “SUMIAN 6” [J];ACTA BOTANICA SINICA;1998-08
3 1CHEN Da Hua 2MENG Yu Ling 1YE He Chun ** 1LI Guo Feng 2CHEN Xiao Ya 1(Department of Cell and Genetic engineering, Institute of Botany, The Chinese Academy of Sciences, Beijing 100093) 2(Nat;CULTURE OF TRANSGENIC ARTEMISIA ANNUA HAIRY ROOT WITH COTTON CADINENE SYNTHASE GENE [J];ACTA BOTANICA SINICA;1998-08
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