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《China Medicine and Pharmacy》 2011-16
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Clinical observation of adjuvant chemotherapy of postoperative gastric cancer by compound Matrine injection combined with DFC chemotherapy regimen

LU Binbin WANG Zhaoxia WANG Juan LI Juan WANG Jirong WANG Keming Department of Oncology,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,China  
Objective To observe and compare the toxicity of compound Matrine injection in combination with DCF regimen(doce taxel+cisplatin+fluorouracil) and DCF regimen in the adjuvant chemotherapy of patients with postoperative gastric cancer. Methods 40 patients with postoperative Ⅱ-Ⅲ stage gastric cancer diagnosed pathologically were divided into compound Matrine injection in combination with DCF regimen group(study group) 20 cases and DCF regimen group(control group) 20 cases.Each patient was given 6 cycles and the toxicity was then evaluated. Results 25 cases could be evaluated in study group and 24 cases could be evaluated in control group. The difference of incidence rates of leucopenia,gastrointestinal,hepatic function and anergy between the two groups was significant(P 0.05) . Conclusion Compound Matrine injection can reduce toxicity in study group significantly while enhancing patients’ tolerance to chemotherapy.
【Fund】: 南京医科大学重点项目(2009NJMUZ21)
【CateGory Index】: R735.2
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 ;岩舒注射液加PF方案治疗有癌穿孔征象食管癌的临床观察[J];Chinese Journal of Oncology;2002-04
2 WANG You-chun,MA Jian-dang.Department of Gastroenterology.the central Hospital of Luoyang,Henan 471009,China;Clinical Observation of Yan-shu Injection Combined with 5-Fu and DDP in the Treatment of Gastric Cancer[J];China Practical Medicine;2009-17
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHONG Wei-wei,HUANG Shu-qing(Hefei Tianyuan Institute of Pharmaceutical,Hefei,Anhui 230031,China);Preparation and content determination of Fuyanxiao Vaginal Tablet[J];Anhui Medical and Pharmaceutical Journal;2012-01
2 LI Lin-xuan,TANG Mei-qiong,LIANG Ying,WEI Kun-hua,MIAO Jian-hua(Guangxi Botanical Garden of Medicinal Pant,Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement,Nanning,Guangxi 530023);Physiological Responses of Sophora tonkinensis Gagnep.Seedlings under Drought Stress[J];Northern Horticulture;2012-10
3 SHEN Yi-hong1 ZHU Jian2 LI Jing2(1.College of Biotechnology,Southwest University,Chongqing 400716,China;2.College of Pharmaceutics,Southwest University,Chongqing 400716,China);Research and Application of Plant Alkaloids in Medicine[J];Newsletter of Sericultural Science;2008-01
4 SONG Chun-Hui,WAN Mo-Bin ,ZHU Wei,GUO Pin-E( Department of Infectious Diseases,Changhai Hospital,Second Military Medical University,Shanghai 200433,China; Department of Laboratory Diagnosis ,Changhai Hospital);Effect of matrine compound injection on interleukin-1β level in serum of rat with liver fibrosis[J];Academic Journal of Second Military Medical University;2003-10
5 ;Determination of matrine and oxymatrine contents in Ganlibao capsule by optimized high performance capillary zone electrophoresis[J];Academic Journal of Second Military Medical University;2008-01
6 JIANG Yi-Deng1, ZHANG Hui-Ping2, CAO Jun1, LI Gui-Zhong1, WANG Shu-Ren3 1Department of Pathophysiology, Ningxia Medical College, Yinchuan 750004, China, 2Department of Gynecology and Obstetrics, Maternal and Child Health Hospital, Yinchuan 750004, China, 3College of Pre-clinical and Forensic Medicine, Sichuan University, Chengdu 610041, China;Effect of matrine on PPAR-γ and caveolin-1 expressions in foam cells derived from monocytes[J];Journal of the Fourth Military Medical University;2007-13
7 LIANG Jian-xin1, QU Xing-fen2, ZENG Wen-ting1, ZHU Ke-lun1, ZHANG He1, WEI Jian-jun1 1Department of Infectious Diseases, First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510120, China; 2Department of Internal Medicine, Shilou Hospital of Panyu District, Guangzhou 511447, China;Mechanism of oxymatrine in preventing hepatic fibrosis formation in patients with chronic hepatitis B[J];Journal of Southern Medical University;2010-08
8 Chang Ronglin, Liu Yiqun , Zhang Zhaoru, et al. Department of Infectious Disuse, First People' s Hospital, Chaohu ,238000 Anhui;Clinical observation on treatment of chronic hepatitis B with combination of matrine and diammonium glycyrrhizinate[J];Journal of Clinical Hepatology;2003-03
9 WU Xiao-luan1, HANG Tai-jun1, SHEN Jian-ping2, ZHANG Yin-di2, XU Zhong-nan3, ZHANG Xi-lai3, ZHANG Lai-fang3 (1. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China;2. Institute of Clinical Pharmacology, Nanjing Medical University, Nanjing 210029, China;3. Jiangsu Chia Tai-Tian Qing Pharmaceutical Co. Ltd., Lingyungang 223220, China);Pharmacokinetics of oxymatrine and its metabolite matrine in healthy volunteers after oral administration of oxymatrine capsule[J];The Chinese Journal of Clinical Pharmacology;2007-01
10 Xu Jin-dan(No.1 Department of Radiotherapy Ward,the Fourth Hospital of Fushun,Fushun 113123,China);The Efficacy Observation of Compound Matrine combined with Chemotherapy in the Initial Treatment of Advanced Gastric Cancer in Elderly[J];Chinese Journal of Medicinal Guide;2012-11
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Li Yong Zhang Xiangru Sun Yan Cancer Institute & Hospital,CAMS & PUMC,Beijing 100021,China;Chemotherapy advances of non-small-cell lung cancer in the recent clinical trials[J];Oncology Progress;2006-04
2 XIONG Liang-geng. Department of Oncology,Dazhou No.2 Hospital,Dazhou,635000;Clinical Observation of Yanshu Injection Combined with Paclitaxel and Oxaliplatin in the Treatment of Advanced Gastric Cancer[J];The Practical Journal of Cancer;2008-03
3 WANG Bing1,WANG Guo-jun2,XU Jun1(1.Department of Radiotherapy,Shanghai Sixth Hospital,Shanghai,200233,China; 2.Department of Infection,Changzheng Hospital,Second Military Medical University,Shanghai,200003,China);Inhibitory effect of Oxymatrine on vascular endothelial cell proliferation induced by tumor[J];JOURNAL OF PRACTICAL ONCOLOGY;2000-05
4 ZHANG Shao-zhong~,XIE Zhe,HUANG Da-ren(Dept.of Oncology,The Second Hospital of Shantou,Shantou 515011,China);Treating Advanced Liver Cancer with Compound Kushen Injection:Clinical Observation[J];Evaluation and Analysis of Drug-Use in Hospitals of China;2008-06
5 Xiao Zefen,Yang Zongyi,Lu Ling,et al.Cancer Hospital, Peking Union Medical College,Chinese Academy of Medical Science,Beijing 100021;Prognostic factors of radiotherapy for perforated esophageal carcinoma(PEC)[J];CHINESE JOURNAL OF RADIATION ONCOLOGY;1997-04
6 ;岩舒注射液加PF方案治疗有癌穿孔征象食管癌的临床观察[J];Chinese Journal of Oncology;2002-04
7 Zhang Liping, Jiang Jikai, Tan Rongan, et al. Department of Clinical Biochemistry, Chongqing University of Medical Science, Chongqing 400046;Effects of matrine on telomerase activity and cell cycle in K562 cell[J];CHINESE JOURNAL OF ONCOLOGY;1998-05
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