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《Industrial Health and Occupational Diseases》 2002-01
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Effect of Low Concentration Manganese on Reproductive Function of Mice

XUAN Deng\|feng,YI Jian\|hua,HUA Wei (School of Public Health,Xian Jiaotong University,Xian 710061 China)  
Objective\ To study the effects of low concentration Mn exposure on male mice reproductive functions.Methods\ The morphology,activity,quantity of sperm,the level of Mn in testicle and the weight coefficient were investigated after a successive 12 weeks i p administration of Mn(2\^5,5,10,20 mg/kg).Results\ Results showed that the quantity,activity and the weight coefficient were significantly decreased as the dose increased.The ratio of sperm deformity and the level of Mn in testicle were significantly increased as the dose increased.Conclusions\ It suggested that low concentration of Mn might have sperm toxicity in mice.
【CateGory Index】: R114
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