Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Industrial Health and Occupational Diseases》 2005-02
Add to Favorite Get Latest Update

Effects of Cerium on Proportion of Internal Organs of Rats and Anti-oxidation Ability in Liver and Kidney

GONG Ju-fang *,ZHANG Zi-gui *,SHEN Xiu-ying *, XU Xiao-lu,CAI Rong-gang * ( * College of Chemistry & Life Sciences,Zhejiang Normal University,Jinhua 321004 China)  
Objective To study some biological effects and mechanisms of cerium on male and female Spraque-Dawley(SD)rats.Methods The rats were fed with cerium-containing solution for a long term,instead distilled water was fed for controls for 5 months.Then the rats were sacrificed to get the ratio of organs to body weight by weighing;the activities of SOD and the contents of MDA in the liver and kidney were detected.Results Compared with the control group,the ratios of lungs to body weight of male rats in three dosages groups increased obviously,(4.1±0.8),(3.7±0.4),and(4.3±1.5)mg/g respectively;while in female rats obvious increase was found only in low and middle dasages groups(P0.05).The ratio of liver to body weight of low dose female rats increased remarkably(33.2±6.3)mg/g.Different effects of cerium on target organs of male and female rats were observed.Cerium could significantly reduce the activities of SOD(P0.05)in liver of three dosages groups,( 3 034.6±566.6),( 3 050.5±456.3),and( 3 083.4±560.3)U/ml respectively.The activities of SOD in kidney of middle and high dosages groups were down obviously(P0.05),while the levels of MDA in liver and kidney had no obvious change.Conclusions Cerium has toxic effects on liver and lung of rats,and could decrease the antioxidation ability of the liver and kidney.
【Fund】: 浙江省教育厅资助项目 ( 2 0 0 2 0 85 3 );; 浙江省大型仪器分析测试基金资助项目 ( 0 2 0 82 )
【CateGory Index】: R114
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 5 Hits
1 WANG Xiu-qin,HUANG Shu-feng,LI Zong-yun.Institute of Cellular and Molecular Biology,School of Life Science,Xuzhou Normal University,Xuzhou,Jiangsu 221116,China;Effect of Ce~(4+)on Activity of SOD and CAT in Drosophila melanogaster[J];Journal of Environment and Health;2007-03
2 WANG Xiu-qin HUANG Shu-feng LI Zong-yun~* (Institute of Cellular and Molecular Biology,School of Life Science,Xuzhou Normal University,Xuzhou 221116,China);Effects of Ce(SO_4)_2 on Life Span and Reproductive Ability of Drosophila Melanogaster[J];Journal of Environmental & Occupational Medicine;2007-06
3 HUANG Shu-feng,LI Zong-yun,HU Fang-fang,FEI Hong-mei(School of Life Science,Xuzhou Normal University,Xuzhou 221116,China);Research Progress on Biological Activity of Rare Earth Element Cerium[J];Journal of Agro-Environment Science;2007-S1
4 HAO Li-ming1,JIANG Wen-hua1,DONG Zhi-yong1,XIA Qing2,CHEN Dong3 (1.Basic Medical Science School,Jilin University,Changchun 130021,China;2.Department of Histology and Embryology,Tianjin Medical Science School,Tianjin 300222,China;3.Department of Histology and Embryology,Guangdong Medical College,Zhanjiang 524031,China);Study of the Mixed Rare Earth Changle on Wistar Rat's Kidney[J];Journal of Xinyang Normal University(Natural Science Edition);2007-04
5 SHI Cui-e,ZHAO Shi-ming,LI Er-qian,WANG Chen,WANG Hao,WANG Cheng-run(School of Life Science,Huainan Normal University,Huainan 232001,China);Effect of La~(3+) on Activities of Antioxidant Enzymes in Aspergillus Niger[J];Chinese Rare Earths;2010-04
【Citations】
Chinese Journal Full-text Database 6 Hits
1 Chen Zuyi,Cheng Wei and Zhang Ligan (College of Science,Nanjing Agric Univ,Nanjing 210095);Study on the concentration of (~(147)Pm) (RE) in herbivorous animal[J];JOURNAL OF NANJING AGRICULTURAL UNIVERSITY;1999-03
2 Liu Yu 1,Chen Zuyi 2 and Wang Yuanxing 1 ( 1College of Animal Science and Technology, 2College of Science,Nanjing Agric Univ,Nanjing 210095,China);Effects of rare earth element cerium(Ce)on abnormality rate of sperms and testosterone secretion in sera of male mice[J];Journal of Nanjing Agricultural University;2001-01
3 Li Liping et al.(Dept .of Public Health, Shandong Medical College, Jinan 515031);Cytoxicity of carbon arc lamp dusts[J];JOURNAL OF HEALTH TOXICOLOGY;1994-02
4 Xiao Renqiu, Zhu Xianghong, Wu Jiaxiang, Wang Xinrei, Shi Bo( Department of Pathology, Basic Medical College, Norman Bethune University of Medical Sciences, Changchun 130021, China );Effects of Low Does SmCl 3 on the Islet of Experimental NIDDM Rats[J];JOURNAL OF THE CHINESE RARE EARTH SOCIETY;1997-03
5 YANG Wei dong 1,WANG Ting 3,LEI Heng yi 2,LIU Jie sheng 1,YANG Yan sheng 2 (1.College of Life Sciences and Biotechnology,Jinan University,Guangzhou 510632; 2.College of Chemistry and Chemical Engineering,Zhongshan University, Guangzhou 510275;Progress in Studies on Biological Effects of Rare Earth[J];CHINESE RARE EARTHS;2000-03
6 Baotou Railroad Sanitation and Antiepidemic station(014040);Effects of the Rare Earth Elements on Cellular Immunity of the Working People[J];CHINA PUBLIC HEALTH;1998-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Ya-li(College of Life Science,Henan Normal University,Xinxiang,Henan 453007);Effect of Methanol and Vc on the Decrepitude of Vicia faba[J];Journal of Anhui Agricultural Sciences;2006-04
2 XU Xiang-gui et al (Department of Biology,Suzhou Science and Technology College,Suzhou,Jiangsu 215009);Effect of Lanthanum on Activity of Isolated Rat's Ileum[J];Journal of Anhui Agricultural Sciences;2006-12
3 REN Chuan-zhong et al(Xinyang Vocational and Technical College,Xinyang,Henan 464000);Effect of Salicylic Acid on the Nitrogen Assimilation and Activity of Defense Enzyme of Chrysanthemum Leaf during the Green Bud[J];Journal of Anhui Agricultural Sciences;2006-14
4 YI Zhao-hui et al (Xinyang Vocational and Technical College,Xinyang,Henan 464000);Effect of SA on the Physiological Change and Florescence of Chrysanthemum[J];Journal of Anhui Agricultural Sciences;2006-17
5 DU Kai-shu et al (Plant Protection Department,Henan Institute of Science and Technology, Xinxiang,Henan 453003);Preliminary Report on the Extraction Technique of Superoxid Dismutase from the Pupae of Apis mellifer[J];Journal of Anhui Agricultural Sciences;2006-23
6 WANG Qi et al(Fushun Teachers College,Fushun,Liaoning 113006);Comparative Study on SOD Enzyme Vitality of the Wild and Cultivated Cordyceps militaris (Fr) Link[J];Journal of Anhui Agricultural Sciences;2008-20
7 ZHOU Jian-qin (Department of Bioengineering,Jiangsu Food Science College,Huaian,Jiangsu 223003);Study on the Breeding and Fermentation Conditions of SOD High-producing Strain from Yeasts[J];Journal of Anhui Agricultural Sciences;2008-31
8 XUE Yan et al(College of Environmental Science and Engineering,Hohai University,Nanjing,Jiangsu 210098);Effects of Cadmium(Cd) on Lipid Peroxidation and 2 Protective Enzymes Activity of Artemisia seleirgensis[J];Journal of Anhui Agricultural Sciences;2009-02
9 LIANG Li-bo 1 ,MA Ye-wei 1 ,ZHAO Qing-zheng 1* ,ZHOU Xiao-shan 1 ,YANG Jun 2 ,LI Yan-chun 1 ,LIU Yu-ying 1 ,WANG Zheng 1 ,ZHAGN Yang-pei 2 1.Cancer Institute,Peking Union Me dical College,Chinese Acade;MnSOD Gene Regulated by Aminopeptid ase N Promoter Specifically Protects Bone Marrow from Radiation[J];Chinese Journal of Cancer;2002-09
10 ZHU Shi dong (Department of Horticulture, Anhui Agricultural University, Hefei 230036);Physiological Effects of Free Radical Scavengers on Senescent Seeds of Vegetables[J];JOURNAL OF ANHUI AGRICULTURAL UNIVERSITY;2001-04
China Proceedings of conference Full-text Database 4 Hits
1 WEI Shan-cheng[1] HAN Xue-yun[1] REN Yu-zhen[2] ZHOU Xiao-yan[1] (1.College of Physics & Information Engineering, 2. Audio-visual Education Center Henan Normal University, Xinxiang 453007, China);The Storage Research of He-Ne laser irradiation Dioscorea Opposita Thunb.cv.Tiegun[A];[C];2008
2 Guo Zhixun Li Zhuojia Lin Heizhao Ye le Feng Juan Yang Yingying Chen Yongqing (South China Sea Fisheries Institute,Chinese Academy of Fishery Science,Guangzhou 510300,China);Effects of the Bacilus sp. on growth and immunity of the white leg shrimp[A];[C];2003
3 Chen Zuyi (Naning Agricultural University, Nanjing, 210095, China);Hormesis-Effects of Rare Earths on Biologys and Its Concealed Effects on Agricultural Eco-Environment[A];[C];2004
4 LI Yan-qiu,SONG Hui,SU Ling (College of Life Science,Jilin Agricultural University,Changchun 130118,China);Anti-oxidative Activity of Polysaccharides from Submerged Fermentation Extractum of Tremella fuciformis[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 QU Ai, WANG Cheng-run, BO Jun, et al (Department of Biology, XuZhou Normal University, Xuzhou 221116,China; Department of Chemistry and Biology, HuaiNan Normal College, HuaiNan 232001, China);Research on DNA Damage in Bone Marrow Cells of Mice in Vivo Induced by Rare-Earth Element Holmium by Means of Singce Cell Gel Electrophoresis[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-06
2 WANG Zhi-hao~1 ZHOU Qing~(1,2) (1 School of Biotechnology,Jiangnan University,Wuxi 214122,Jiangsu,China;2 The Key Laboratory of Industrial Biotechnology,Ministry of Education,Jiangnan University,Wuxi 214122,Jiangsu,China);Influence of terbium on horseradish at different concentrations[J];Journal of Safety and Environment;2007-06
3 Li Qi College of Forest Resources and Environment, Beijing Forestry University, Beijing 100083, P.R.China Shen Yingbai Wang Shasheng * The Experimental Center of Forest Biology, Beijing Forestry University, Beijing 100083, P.R.China;X-ray Microanalysis of Ce and Ions Contents in Stem Tip Meristem and Leaves of Populus deltoides Bortr c.v. “Lux" Grown in Nutrient Solutions with Different Level of Ce(NO 3) 3 Treatment 1[J];北京林业大学学报(英文版);1996-02
4 Zhu Shigong 1,Hua Kun 1,Xia Yinghong 2,Wang Shao 2 (1\ Dept.of Pathophysiology;2\ Dept of Physiology,Basic Medical School, Norman Bethune University of Medical Sciences);Effect of LaCl 3 on electrophysiologic activity of ARCN,DMN and VMN[J];JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE;1999-04
5 DONG Zhi yong, CHEN Dong, LIU Ying,CHEN Ai jun,LIU Jia mei,Nie Yu xiu (Dept. of Histology and Embryology,School of Basic Medical Sciences, Jilin University, Changchun 130021, China);Effect of Mixed Rare Earth Changle on Calcium Content and it′s Deposition in the Liver of Pregnant and Fetal Rats[J];Journal of Norman Bethune University of Medical Science;2003-01
6 HUANG Ke xin 1,LI Dong mei 2,LI Shu lei 1,NIE Yu xiu 1 (1. Dept.of Histology and Embryology,School of Basic Medical Sciences,Jilin University, Changchun 130021, China;2. Dept.of Special Education,Changchun University) [;Effects of a Long-term Administration of Low Dosage La(NO_3)_3 on SOD and LPO in Rat Hearts[J];Journal of Jilin University of (Medicine Edition);2003-05
7 XIA Qing ,CHEN Dong *,DONG Zhi yong (Department of Histology and Embryology, School of Basic Medical Sciences, Jilin University, Changchun 130021, China);Effect of the mixed rare earth Changle on hepatic enzymatic activity of rat[J];Journal of Jilin University of (Medicine Edition);2004-01
8 Lei Zhiming Department of Health Toxicology;A PRACTICAL MULTIPLE IMMUNOASSAY IN A SINGLE ANIMAL[J];;1991-05
9 LI Rongchang △, YANG Huiwen, WANG Kui (Department of Chemical Biology, Peking University School of Pharmaceutical Science,Beijing 100083,China);La accumulation and microstructure change of leg bones of rats fed with La(NO_3)_3 in low dosage for a long term[J];Journal of Peking University(Health Sciences);2003-06
10 CHEN Juntao*, LI Xinjun*, YANG Ying, WANG Liangyan, HE Mingxing (Guangzhou Institute of Energy Conversion, The Chinese Academy of Sciences, Guangzhou 510640, Guangdong, China);Effect of Sm ~(3+) Doping on Photocatalytic Properties of TiO_2 Thin Films[J];Chinese Journal of Catalysis;2004-05
China Proceedings of conference Full-text Database 1 Hits
1 HUANG Yao, ZHANG Zhao-jian, HUANG Yu-fang (National Microanalysis Center, Fudan University, Shanghai 200433, China);Analysis of Trace Elements in Ancient Human Bones by Inductively Coupled Plasma Mass Spectrometry[A];[C];2004
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 WANG Xin, LU Lu,YE Jing-bo,et al. School of Life Sciences,Sun Yat-sen University,Guangzhou,Guangdong 510275,China;Antagonistic Effects of Ganoderma Spore on Mutation Induced by Sodium Nitrite in Drosophila melanogaster[J];Journal of Environment and Health;2009-07
2 ZHAO Pan-feng 1,WANG Qing-xiang2,WANG Na-na2,JIANG Wen-chun2,LIANG Yi2(1.School of Agriculture and Biology,Shanghai Jiaotong University,Shanghai 200240,China;2.College of Agronomy,Shenyang Agricultural University,Shenyang 110013,China);Effect of the Rare Earths La,Ce,Gd on Maize Seedling Physiological Indexs[J];Acta Agriculturae Boreali-Sinica;2010-S2
3 LIU Xi-hao,TIAN Yin-yan,JIN Li-cai,YU Yu-feng,SHAO Ying(School of Chemistry and Chemical Engineering,Shaoxing University,Shaoxing 312000,China);Bis-salicylaldehyde O-phenylenediamine Cerium(Ⅲ) Complex and its Bioactivity[J];Shandong Chemical Industry;2009-11
4 WANG Yan1,NIE Guang-hua1,DAN You-meng1,YANG Yi-xin2(1.College School of Chemical and Environmental Engineering,Hubei University for Nationalities,Enshi 445000,China;2.Department of Chemistry,Northwest University,Xi'an 710069,China);Synthesis,Characterization and Properties of Rare Earth Complex Nd(C_5H_8NO_3)_2(C_3H_5N_2)_2Cl_3·4H_2O[J];Journal of Xinyang Normal University(Natural Science Edition);2009-02
5 FEI Hong-mei, YANG Su-chun, LUO Juan, LI Zong-yun (Institute of Cellular and Molecular Biology, School of Life Science, Xuzhou Normal University, Xuzhou 221116, China);Rare Earth Element Cerium Induced hsp70 mRNA Expression in Root Tip Cells of Maize[J];Journal of Maize Sciences;2010-03
6 SHI Cui-e,ZHAO Shi-ming,LI Er-qian,WANG Chen,WANG Hao,WANG Cheng-run(School of Life Science,Huainan Normal University,Huainan 232001,China);Effect of La~(3+) on Activities of Antioxidant Enzymes in Aspergillus Niger[J];Chinese Rare Earths;2010-04
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Wang Yuzhen;Han Ziying;Zhou Aimin; et al.(Department of microleology,Baotou Medical College,Baotou 014010);Preliminary Study on the Results of PHA Skin Tests in Different Age Groups of the Children Between the Mongols and the Hans[J];JOURNAL OF BAOTOU MEDICAL COLLEGE;1995-04
2 FENG Zhi-Xiang, ZHANG Shu-Gong , LIU Qi-MinYANG Kui-Yue, NI Jia-Zuan(Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Chanchun, 130022)MIAO Jian, YOU Shu-Heng (Department of Biochemistry, Henan Medical University, Zhengzhou);Interactions of Rare Earth Ions with Bovine Blood Cu(Zn)-Superoxide Dismutase[J];Chemical Research In Chinese Universities;1995-07
3 HUANG Zhong-Xian;ZHENG Qi;GAO Hong-Ying;GU Wei-Qiang;LIU Fang(Department of Chemistry,Fudan University,Shanghai,200433);The Reactions Between Lanthanons and Metallothionein[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1996-02
4 YANG Bin-Sheng(Institute of Molecular Science, Shanxi University, Taiyuan, 030006)T. G. St.Pierre, J. Webb(Murdoch University, Perth WA6150, Australia);The Effect of Europium (Ⅲ) on Iron Uptake by Apoferritin[J];CHEMICAL RESEARCH IN CHINESE UNIVERSITIES;1996-05
5 Xiao Bangliang (School of Public Health, West China Univ. of Medical Science, Chengdou, Sichuan, 610041, China);THE LUNG GRANULOMA INDUCED BY THE POWDER OFYTTRIA AND ITS MINERAL IN RATS ——OBSERVATION ON HISTOPAT HOLOGY AND ENZYME[J];Industrial Health and Occupational Diseases;1992-02
6 Zou Tongtong (School of Public Health, Beijing Medical Univ., 38, Xueyuan Rd., Beijing, 100083, China);THE INVESTIGATION OF CYTOTOXICITY OF FIVE RARE-EARTH DUSTS[J];Industrial Health and Occupational Diseases;1992-02
7 Lu Guocheng et al.(Dept. of Environ.Health, Beijing Medical University, Beijing 100083);Hygienic Investigation of Different Rare Earth(RE) Mining Areas in China: RE Levels of Farmer's Natural Living Environment and Head Hair[J];CHINESE JOURNAL OF ENVIROMENTAL SCIENCE;1995-04
8 ZHANG Peiqun; LU Xiangli; QIAN Qinfang; FENG Weiyue (Institute of High Energy Physics, the chinese Academy of Sciences, Beijing 100080)GUI Zhong ZHANG Geyou DAI Qin REN Xianyun LIANG XiufenZHANG Meiyun (Huhhot Health and Anti- epidemic Station, Huhhot,;Study of trace element contents in scalp hair of the juveniles from the arsenism area in Inner Mongolia[J];NUCLEAR TECHNIQUES;1998-06
9 Liu Fengzhen, et al;Preliminary Study on ADI of Aluminium of Chinese[J];Journal of Environment and Health;1991-02
10 Cui Li;Nie Yuxiu;Yin Xin;Chen Yulan Department of Histology and Embryology,Norman Bethune University of Medical Sciences,Changchun 130021;ELECTROMICROSCOPIC OBSERVATION OF THE EFFECTS OF SAMARIUM CHLORIDE ON RAT ADENOHYPOPHYSEAL CELLS[J];Chinese Journal of Anatomy;1993-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved