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《Journal of Guiyang Medical College》 2002-01
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A Clinial Study on the Treatment of Hemifacial Spasm, Blepharospasm and Meige Syndrome with Botulinum Toxin A

XU Jian (Department of Health Care of Cadre and Neurology, Affiliated Hospital of Guiyang Medical College,Guiyang 550004 ,China)  
Objective:To explore the curative effect of Botulinum toxin type A(Botox)on hemifacial spasm(HFS),blepharospasm(BS) and Miege syndrome. Methods:Twenty six patients with HFS,twelve patients with BS and four patients with Meige syndrome were treated with Botox injections at many points of local spasmatic musles .Symptomatic alleviations after the injection were graded and the conditions were compared with the symptoms pretreatment. Results:Of the forty two patients ,thirty eight(90.5%) were remarkably alleviated ,four(9.5%)were partially alleviated.The duration of the effect was 9 to 25 weeks.Five patients were injected repeatedly.The duration of the effect was shorter and shorter and injection dose was gradually increased for these patients.The local side effects were transient and mild. No systemic adverse and allergic reaction were noted. Conclusion: This study shows that the therapy is safe ,effective,simple and easy to apply. Botox can be used as first selection for uhe treatment of HFS,BS and Meige syndrome.
【CateGory Index】: R742.05
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