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《Journal of Guiyang Medical College》 2002-02
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Content Changes of the Serum Albumin in Rats with CCl_4 Induced Liver Fibrosis

XU Qing zhong, LEI Ting wen, MA Xiao ping (Departmant of Biochemistry and Molecular Biology, Guiyang Medical College,Guiyang 550004,China)  
Objective:To observe the change of serum albumin in live fibrosis. Metheds: Rat liver fibrosis was induced by CCl *#4.The contents of serum albumin and liver collagen were measured in 2?4?6 and 8 weeks after treatment. Results: The contents of serum albumin decreased and Hepatic collagen increased singnificantly in two weeks after treatment, then ,the serum albumin increased ,but decreasd again at the 8 th week.Hepatic collagen kept the same level at the 4 th ,6 th ,and 8 th weeks post-treatment. Conclusions: The serum albumin levels might be an good indicator of early liver fibrosis and its prognosis.
【CateGory Index】: R575.2
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