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Experimental Study of the Effect of Perilla frutescens Seed on Hyperlipoidemia Model Rats

WANG Yu,LIU Jia,GAO Min,YU Hong,WU Ke-feng,RUAN Hai-xing,ZHU Cai-lin(Guizhou Provincial Center for Disease Control and Prevention,Guiyang 550004,China)  
Objective: To study the blood lipid reducing effect of Perilla frutescens seed in hyperlipoidemia model rats.Methods: Rats in treatment groups were continually given P.frutescens seed at doses of 0.8,4.2,25.0g/kgBW separately for 30 days.The serum levels of TC,TG and HDL-C of rats were examined on the 30~(th) day.Results: The serum contents of TC and TG in treated rats were markedly less than those of non-treated model group,while the level of HDL-C was not reduced.Conclusions: P.frutescens seed could reduce the level of blood lipids,except HDL-C,in rats.
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