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The Ultrastructural Studies and Sterelogical Analysis on the Epithelial Cells of the Epididymal Ducts of the Mice with Chronic Cadmium Intoxication

Xu Tingliang,et alDepartment of Histology and Embryology,Guiyang Medical College  
he ultrastructures of the epithelial cells of the epididymal ducts of the mice with chronic cadmium intoxication were observed under transmission electron microscopy and were analysed with morphometric techniques.The results showed that the principal cells were obviously injuried.There were clear degenerative changes in the principal cells.The volume of the nucleus was reduced.The mitochondria were swollen and the cristae were broken.The rough surfaced endoplasmic reticula were expanded.The number of the lysosome was increased.A few of the principal cells were found out nicrosis and dissolution.On the other hond,the tight junctions between the principal cells were disappeared and bloodepididymis barrier was disrupted.We considered that the epididymis was a target attacked by cadmium in mice in chronic cadmium intoxication.And,abnormality of the structures and functions of the epididymis would influence the male reproductive function
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