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《Guangxi Medical Journal》 2004-10
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Clinical significance of cerebrospinal fluid Treponemal Antibody tests in patients with latent syphilis

WU Chang-hui ,MA Ze-lin ,CHEN Shu-wen,et al.Zhongshan Preventing Institute for Skin diseases (Zhongshan 528402),P R of China.  
Objective To measure the Treponemal hronic Diseases Antibody in CSF of latent syphilitic patients,and investigate it's clinical significance to the diagnosis of asymptomatic neurosyphilis.Methods Routine test and Treponemal antibodies tests(RPR、VDRL、FTA-Abs、TPHA and TP-IgM) were measured in cerebrospinal fluid of 60 latent syphilitic patients.Results 63.3% had elevated protein concentration and 30% had elevated glucose concentration in CSF. Treponemal antibodies tests: 29(48.33%) had Treponemal antibodies in CSF: 2(3.33%)VDRL, 6(10%)FTA-Abs、7(11.67%)TP-IgM and 14(23.33%)TPHA were positive; there were significantly differences among these four methods measured in CSF.Conclusion CSF Treponemal antibodies tests are helpful in diagnosing asymptomatic neurosyphilis of latent syphilitic patients, and these are significant to the treatment of latent syphilitic patients.
【CateGory Index】: R759.12
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