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《Guangxi Medical Journal》 2009-06
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A Study on the Extract of Adlay Seed for the Inhibition of Nasopharyngeal Carcinoma Cell Lines' Proliferation

LIU Jin,TANG An-zhou,KANG Min,JIANG Yan,DENG Peng(Department of Otolaryngology and Head and Neck Surgery,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)  
Objective To investigate the inhibition of adlay seed on nasopharyngeal carcinoma cell lines CNE1,CNE2,TWO3 and C666-1 in vitro culture.Methods To prepared the extracts of adlay seed and the serum obtained from mice treated orally with extracts of adlay seed.MTT assay was used to examine the effect of the extracts of adlay seed and the serum on the proliferation of CNE1,CNE2,TWO3 and C666-1 cell.Apoptosis of CNE1,CNE2,TWO3 and C666-1 cell were investigated further by means of inverted microscope.Results Adlay seed inhibited the proliferation of CNE1,CNE2,TWO3 and C666-1 cells and the effects were in a time-and-concentration dependent manner.Conclusion The experiments in vitro show that adlay seed can inhibit the proliferation of NPC cells.
【Fund】: 广西科学研究和技术开发计划项目(桂科攻0322024-1A)
【CateGory Index】: R739.63
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