Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Guangxi Medical Journal》 2014-02
Add to Favorite Get Latest Update

Effect of Hypothermia on Brain Function after Cardiopulmonary Resuscitation

WEI Qing-feng;DING Guang-yu;ZHANG Yi;Department of Emergence,the Second Affiliated Hospital,Guangxi University of Science and Technology;  
Objective To explore the protective effect of hypothermia on the brain function after cardiopulmonary resuscitation. Methods Forty-eight patients with cardiac arrest were divided into hypothermia group and normothermia group randomly. The patients in normothermia group were given conventional emergence treatment for cardiac arrest. The patients in hypothermia group were given 4℃ Riger's solution together with physical cooling on the head and neck on the basis of conventional treatment,and the temperature of anus ranged between 33℃ and 35℃. The serum levels of lactic acid in artery,Glasgow coma scale( GCS) scores were measured 24,48,72 hours after cardiopulmonary resuscitation in both groups. The follow-up lasted for 3 to 6 months,the recovery of patients' brain function was observed. Results The serum levels of lactic acid were significantly lower,and the GCS scores were significantly higher in hypothermia group in contrast with those in normothermia group 24,48,72 hours after cardiopulmonary resuscitation,respectively( P 0.05). During the follow-up,the efficacy of patients in hypothermia group was better than that in normothermia group( P 0.05). Conclusion The early application of hypothermia in cardiopulmonary resuscitation is able to alleviate the damage to brain tissue induced by hypoxia-ischemia and improve the prognosis of nerve function.
【Fund】: 广西医药卫生科研课题(Z2013139)
【CateGory Index】: R605.974
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved