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《Chinese Journal of Bone Tumor and Bone Disease》 2004-06
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The preliminary investigation of operation in conjunction with adjuvant postoperative radiation therapy in the treatment of recurrent pigmented villonodular synovitis

XIAO Yanbin, XU Jianbo, YANG Yi, et al. Department of Orthopaedics, The Third Affiliated Hospital of Kunming Medical College, Kunming, 650118, China  
Objective To investigate therapeutic effect of operation in conjunction with adjuvant postoperative radiation therapy in the treatment of recurrent pigmented villonodular synovitis.Methods From April 1998 to April 2003, 10 cases of recurrent PVS were treated by open synovectomy and adjuvant postoperative radiation therapy. Adjuvant radiation was performed 3-4 weeks postoperatively; the dose of radiation was 4550cGy/5W ( 3600- 5600cGy).Results The mean follow-up time was 38 months (13-65 months). All patients were followed by taking repeated computerized tomography scans and plain X-ray films and no local recurrence was found; 1 patient lost the stabilization of his cubital articulation; 1 patient lost some degree of knee motion (0°~95°). In 8 patients, no complications were noticed after surgery or after the radiation therapy. There was no evidence of disease and progression of bone or articular destruction found in all patients.Conclusion Pigmented villonodular synovitis is a difficult tumor to eradicate. A combination of open synovectomy with external beam radiation for recurrent pigmented villonodular synovitis is a reliable method of treatment with good results.
【CateGory Index】: R687
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