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《Guizhon Medical Journal》 2001-01
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The correlation analysis of the gene expression of nm23 between differentiation and prognosis on carcinoma of prostate

Chen Ning, Zhang Bixia, Department of Pathology, the 44th Hospital of PLA, Guiyang,550009  
Objective To analyze correlation of the gene expression of nm23 between differentiation and prognosis on carcinoma of prostate. Methods The nm23 gene protein of 52 cases carcinoma of prostate in differentitation (29 of them were follow-up surveied for five years) and 10 prostate hyperplasia were determined by immunohisto-chemistry.Results The gene expression of nm23 on hyperplasia of prostate were 100%, the carcinoma of prostate were 34/52 (65.38%),the well-differentiatied were 28/32 (87.5%),the bad-differentiated were 6/20 (30%). The two groups showed highly staistical significant ( P 0.01). Among the 9follow-up survey,thegroup of living more than five years were 17/19(89.47%),the group of living less than five years were 30%(3/10)(0.01 P 0.05). Conclusion The correlation between carcinoma of prostate differentiation and well-prognosis was positive correlation.
【CateGory Index】: R737.25
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