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Study of Hematocrit as a predictable marker for Early Severe Acute Pancreatitis

Tang Keli, Cheng Jianhua, Gao yuzhe et al. Guizhou provincial People's Hospital Guiyang, 550002  
Objective To study the feasibility of hematocrit(HCT) as a predictable marker for early severe acute pancreatitis. Methods 32 healthy Wistar rats were randomly divided into 4 groups. Sham operative group(SO), mild acute pancreatitis group(MAP), severe acute pancreatitis group(SAP) and liquid therapy group that each group were divided into 2h, 7h, 12h sub-group again. After models were induced, the serum concentration of amylase(AMY), HCT were tested and observed of pathologic result of the heart, lung, liver, kidney and pancreas. Results (1) HCT had apparently increase in SAP 7h, 12h sub-group compared to 2h(P<0.01), and HCT also had apparently increase in SAP 12h sub-group compared to 7h(P<0.01). (2) In liquid therapy group, HCT had decrease compared 2h to 12h(P<0.01). HCT increase significantly in SAP group, compared to SO, MAP, and liquid therapy group respectively(P<0.01). (3) Wistar rats had no important organ injury in SO, MAP groups, but had some important organs injury in SAP group. Conclusion HCT was an important early predictable marker for SAP.
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