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《STRAIT PHARMACEUTICAL JOURNAL》 2000-02
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Resistance on genetic toxicity of Cyclophosphamide by(Liuwei Dihuang Decotion)

Wang Mingli,Zhao Fengming, et al (Third Hospital Attached to Su Zhou Medical College,213003)\;  
in this experiment Liuwei Dihuang Decotion was tested to resist genetic toxicity of cycolphosphamide CTX,taking the ICR pure mice marrowy cell in vivo as experimental method,sister chromatid exchange(SCE)and micronucleus(MN)as the sign of resistant effect To study the mechanism of resistance,SOD is used as index The result shows that Liuwei Dihuang Decotion can evidently prevent the increase of the mouse bone marrow MN、SCE ratio caused by CTX Raising activation of SOD may be the main cause
【CateGory Index】: R285
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