Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Strait Pharmaceutical Journal》 2006-04
Add to Favorite Get Latest Update

RP-HPLC Determination of Content of Paracetamol in Paracetamol controlled-release Tablets

ZHU Le-kai,Wu Wei-ming,Bao Shi-hui(The Second Affiliated Hospital of Wenzhou Medical College,Wenzhou,325027;China)  
OBJECTIVE To establish HPLC method for the determination of paracetamol in Paracetamol controlled-release tablets.METHODS Using HYPERSIL ODS-C_(18) column(4.6mm×250mm,5μm),methanol-water(52∶48) as the mobile phase.The flow rate was 1.0mL·min~(-1);detection wavelength was 254 nm.Using the method of standard curve.RESULTS The calibration curve was linear in the range of 2.04μg·mL~(-1)~20.40μg·mL~(-1) for geniposide(r=0.9999).The average recovery was 100.06%,and RSD was 2.30%(n=9).CONCLUSION The method is simplicity,accurate,sensitive,reproducible and is suitable for the content determination of paracetamol in Paracetamol controlled-release tablets.
【CateGory Index】: R927.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 5 Hits
1 Wang Ping Zao zhuang City Shan dong THREENINE Pharmacy Co.Ltd.277100;DETERMINATION OF THE CONTENT OF PARACETAMOL IN GONMAOLING GRANULES BY UV[J];Drug Stanoaros of China;2002-05
2 Liu Xinyu and Hou Meiqin (Shanghai Institute for Drug Control,200233);Study of Determination of Compound Common Cold Prepations by HPCE[J];CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS;1997-05
3 QU Aitao,SUN Limin,WEN Aiping,LIU Shuang(Inner Monglia Medical College,Hohhot010059);Determination the Contents of Paracetamol and Caffeine in999Ganmaoling Granules With TLC[J];China Pharmacy;2003-06
4 XUE Hong-yuan,LIU Jian-fang,LIU Hui-chen,WANG Gang,LU Wang-bo (Department of Pharmacology, Bethune International Peace Hospital, Hebei Shijiazhuang 050082, China);Simultaneous determination of paracetamol and caffeine in human plasma by HPLC[J];Chinese Journal of Hospital Pharmacy;2005-08
5 XU Feng, L(U)·· Ya-ping, HU Wei-xiao(College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310032, China);Determination of paracetamol in tablets of bufferin,tylenol and saridon by HPLC[J];Journal of Zhejiang University of Technology;2005-03
Chinese Journal Full-text Database 10 Hits
1 CHEN Jun(Ningbo Institute Pharmaceutical of Control,Ningbo 315040);Determination of paracetamol in jingzhi yinqiao jiedu capsules by HPLC[J];Anhui Medical and Pharmaceutical Journal;2006-02
2 XIONG Xun-yu1,TANG Yu-hai*1,WANG Nan-nan1 and WU Shi-jie2(1.Institute of Analytical Science,Xi′an Jiaotong University,Xi′an 710061;2.College of Chemisitry,Lanzhou University,Lanzhou 730000);Determination of paracetamol by flow-injection chemiluminescence with KMnO4-Na2SO3 system[J];Chinese Journal of Analysis Laboratory;2007-02
3 LIU Li-hong1,PAN Zhi-heng2,ZHU Hai-jing1,MA Ping1,LI Peng-fei1,DING Chun-lei1,TONG Wei-hang1(1. Pharmacy Department of The Second Artillery General Hospital,Beijing 100088,China; 2 School of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China);Determination of paracetamol and dextrochlorpheniramine concentrations in human urine after oral administration by LC-MS/MS[J];The Chinese Journal of Clinical Pharmacology;2009-05
4 LI Peng-Fei①,LIU Li-Hong,MA Ping,DING Chun-Lei,TONG Wei-Hang,YANG Jing-Yan,LAN An-Jie(①General Hospital of the Second Artillery,Beijing 100088 China);Simultaneous Determination of Paracetamol and Dextrochlorpheniramine in Human Plasma by LC-MS/MS[J];Pharmaceutical Journal of Chinese People's Liberation Army;2009-01
5 SHU Xiao-mei~1,YANG Zhi-wen~2,FU Da-hua~2(1.Department of Pharmaceutics,the Third Affiliated Hospital of Nanchang University,Nanchang 330006,China;2.Faculty of Pharmacy,NanchangUniversity Medical College,Nanchang 330006,China);The Preparation of Paracetamol Clear Gum Microsphere and the Study of Its Delayed Releasing Effects[J];Acta Academiae Medicinae Jiangxi;2005-06
6 CHENG Wei QIN Feng LU Xiu-mei BI Yu-jin LI Fa-mei (Department of Pharmaceutical Analysis,School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);Pharmacokinetics of paracetamol and caffeine in paracetamol,caffeine,atificial cow-bezoar and chlorphenamine maleate capsules in healthy volunteers[J];Chinese Journal of Clinical Pharmacy;2007-05
7 Yang Bingyi, Mo Jinyuan, Yang Xiaoyun, Wang Lishi (School of Chemistry and Chemical Engineering, Zhongshan University, Guangzhou 510275, China);Separation and Determination of the Ingredients of Cold Medicines by Capillary Electrophoresis with Amperometric Detection[J];CHINESE JOURNAL OF CHROMATOGRAPHY;1999-05
8 LIU Wei,LU Shan,QIN Feng,GAO Gui-hua,CHEN Ling-yun,LI Fa-mei(School of Pharmacy,Shenyang Pharmaceutical University,Shenyang 110016,China);Simultaneous determination of the contents of paracetamol,salicylic acid and caffeine in human plasma by HPLC[J];Journal of Shenyang Pharmaceutical University;2009-07
9 XU Jian-wen,ZHANG Guang-jun,CHEN ZHeng-yue (Department of Pediatrics,Third Hospital, Xinxiang Medical College, Xinxiang City 453003, China);Study on the infra-red spectrum of the mixture of paracetamol and naproxen[J];Journal of Xinxiang Medical College;2002-04
10 Yin Cha and Wu Yutian (Department of Drug Analysis,School of Pharmacy,Second Military Medical University,Shanghai 200433);Determination of Active Constituents in V_ C Yinqiao Tablets by Micellar Electrokinetic Capillary Chromatography[J];CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS;2000-01
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 Guan Yanqiong Yang Huirong Chen wenqing Li Feng Liao Zhiyun (Dept. of Chemical Engineering, GDUT, Guangzhou, 510090);Study on Synthesis of Paracetamolum[J];JOURNAL OF GUANGDONG UNIVERSITY OF TECHNOLOGY;1997-02
2 YANG Jun-yi,JIANG Xue-hua,LIN Shu,LIN Yu-lian,ZHOU Jing,LAN KeWest China School of Pharmacy,Sichuan University,Chengdu 610041,China;Simultaneous determination of paracetamol and caffeine in plasma by RP-HPLC[J];West China Journal of Pharmaceutical Sciences;2003-02
3 Dai Qun, Zhang Hong, Xu Wenwei, Xong Yuqin (Institute of Clinical Pharmacology, Jiangxi Medical College, Nanchang 330006);Investigation of bioequivalence of paracetamol/caffeine granules in human body[J];Chinese Journal of Clinical Pharmacy;2001-04
4 Wang Yong and Feng Guokang(Fujian Institute for Drug Control, Fuzhou, 350001)Tang Genyuan and Wu Hongjing(Fujian Institute of Research on Structure of Matter, the Chinese Academy of Sciences, Fuzhou, 350002);Determination of Chlorpheniramine Maleate, Acetaminophen,DL-Methylephedrine HCl and Caffeine in Relecold Capsules by High Performance Liquid Chromatography (HPLC)[J];CHINESE JOURNAL OF CHROMATOGRAPHY;1996-04
5 Jin Jianzhong (Inner Mongolia Institute for Drug Control,Huhehaote,010020) Wang Zhanguo (Tong Liao General Pharmaceutical Factory,Tong Liao,028007);HPLC Determination of Three Main Component in Paragesicum Tablets[J];CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS;1997-01
6 Fu Guanghua, Lou Ping and Sun Chengkao (Institute for Drug Control of Liaocheng City, Shandong Province, 276000);Determination of Acetaminophen and Coffeine of New Compound Folium Isatidis Tablets by HPLC[J];Chinese Pharmaceutical Affairs;2003-02
7 HU Zheng Bo,LI Hang,WANG Hai,et al (the 452 Hospital of PLA,Shichuan Chengdu 610021) [;Determination method for paracetamol and caffeine in Likeshu capsules by HPLC[J];Chinese Journal of Hospital Pharmacy;2000-11
8 Yang Fuguo Fang Zheng (Department of Chemistry, Central South University of Technology, Changsha, 410083, China);DETERMINATION OF PARACETAMOL IN CAPSULE FOR COLD BY HPLC[J];;1997-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved