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《Strait Pharmaceutical Journal》 2009-06
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Progress in studies of antioxidative mechanism of flavonoids extracted from Scutellaria baicalensis Georgi in tissue injury

GAO Ping-zhang1,WU Hong1,HUANG Jun-lai,GAO Zhong-hong2(1.The key Laboratory of Molecular Biology &Medicinal Chemistry for Fujian higher education,Quanzhou Normal University,Quanzhou 362000,China;2.Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica,Huazhong University of Science & Technology,Wuhan 430074,China)  
The progress in the research of antioxidative mechanism of flavonoids extracted from Scutellaria baicalensis Georgi was summarized,which provides the theory basis to development new antioxidative traditional Chinese drugs.It was demonstrated by pharmacological experiments that Scutellaria baicalensis Georgi and its extracts exhibited significant antioxidative and free-radical scavenging activities in tissue injury-including cardiomyocytes injury,liver injury,brain injury and neurocytes injury.Scutellaria baicalensis will be exploited to new antioxidative traditional Chinese drugs,however,the detailed antioxidative mechanism in vivo would study in future.
【Fund】: 国家自然科学基金项目(NO.30670481);; 福建省教育厅科技项目(NO.JA08209);; 泉州师范学院校级自选课题项目(NO.2008KJ11)
【CateGory Index】: R285.5
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