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《Strait Pharmaceutical Journal》 2010-02
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Antioxidant activity of extracts from radix and cauliset Polygonum multiflorum Thunb.

SHEN Hui1,LIN Qiang2(1.Nanjing secondary technical school of medicine and pharmacy Nanjing 210000,China;2.Adverse drug reaction monitoring center of Fujian Province Fuzhou,350001,China)  
OBJECTIVE To evaluate the total antioxidant activity of extracts from Polygonum multiflorum Thunb.in vitro.METHODS 1,1-diphenyl-2-picryl-2-picrylhydrazyl(DPPH)radical scavenging,〔2,2'-azino-bis-3-ethylbenzothizaoline-6-sulfonic acid〕diammonium salt(ABTS)radical scavenging,and ferric reducing antioxidant power(FRAP)assay were used to analyze the antioxidant activity.RESULTS Compared with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid(Trolox)and positive control 2,6-di-tert-butyl-4-methylphenol(BHT),the ethyl acetate extract and the methanol extract from roots showed higher scavenging activity against DPPH radical,ABTS radical,and reducing antioxidant power of TPTZ.CONCLUSION The antioxidant activity of roots was higher than that of stems.In six extracts of P.multiflorum Thunb.,the ethyl acetate extract of roots showed highest total antioxidant activity.In the same part,the methanol extract and the ethyl acetate extract showed higher total antioxidant activity than that of the petroleum ether extract.The results among the three methods were consistent,and the values obtained by DPPH assay were correlated best with those obtained by ABTS assay(R=0.996).
【CateGory Index】: R285
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