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Avermectin Component B_(1a) Analysis of Spaceship Carrying Strains

SU Wei,LU Zhi-tang,WANG Hong-bin,ZHANG Li-ping(College of Life Sciences,Hebei University,Baoding 071002,China)  
After Streptomyces avermitilis HY1 come back from spaceship carrying,24 strains with high productivity and stable genetics were screened out by two rounds screening.Their avermectin titers all increased over 24% and the highest one reached 83%.2 strains,HY365 and HY516,with high ratios of validation component B-(1a) were obtained by HPLC determination.Strain HY365 has total tilter of 5 924.7 mg/L and(3 894.8 mg/L) of B-(1a) component,65.74% of the total titer.And strain HY516 has total tilter of 5 262.0(mg/L) and 3 151.9 mg/L of B-(1a) component,59.90% of the total titer.
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