Full-Text Search：
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Hubei Medical University》 2003-02
Add to Favorite Get Latest Update

Therapeutic Effect of Garlic Polysaccharide onCoxsackie B_3 Viral Myocarditis in Mice

Cai Fei, Chen Jinhe, Wu JiliangDepartment of Pharmacology, School of Medicine, Wuhan University, Wuhan 430071, China  
Objective: To investigate the therapeutic effect of Garlic Polysaccharide on experimental mice viral myocarditismodel caused by coxsackievirus B 3(CVB 3). Methods: Viral myocarditis model was created by intraperitoneal inoculation with coxsackievirus B 3 solution and mice were randomly devided into four groups: the normal control group,the model control group,the Garlic Polysaccharide group(GP group) and the Astragalus membranaceus group(AM group).The mice of GP group and AM group were treated by Garlic Polysaccharide and Astragalus membranaceus respectively 1 h after CVB 3 infection.Blood and heart samples were obtained on the 8th day after CVB 3 infection. The survival rate and the myocardial histopathologic changes were observed. The serum cardiac enzyme,the content of MDA,the serum NO level, the GSH Px activity,the virus title of heart and the expression of iNOS were also measured. Results: The survival rate,the GSH Px activity of GP group were higher than those of the model control group.The myocardial damage, the serum cardiac enzyme,the content of MDA,the serum NO level,the virus title of heart and the expression of iNOS of GP group reduced more significantly than those of the model control group. Conclusion: Garlic Polysaccharide may have the therapeutic effect on experimental mice viral myocarditis model caused by CVB 3.
【Fund】： 湖北省教育厅资助课题 ( 2 0 0 1B44 0 0 1)
【CateGory Index】： R542.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 LIU Chao-qun1,CHEN Jing1,HUANG Xue-song2,CHEN Cui-tao1,WU Wei-qing1(1.Department of Nutrition,College of Medicine,Jinan University,Guangzhou 510632,China; 2.Department of Food Science and Engineering,College of Science and Engineering, Jinan University,Guangzhou 510632,China);Protective effects of garlic polysaccharide on liver injury in mice with chronic alcoholism[J];Journal of Jilin University(Medicine Edition);2012-01
2 ZHOU Jinghua1,LI Hanwei2,WAN Shunkang1,ZHANG Cuixiang1(1.Pre-clinical College,Dali University,Dali,Yunnan 671000,China; 2.Dali Affiliated Hospital of Dali University,Dali,Yunnan 671000,China);Research Review into the Polysaccharide Structure and Biological Activity of Garlic[J];Journal of Dali University;2010-12
3 Wenling Wang, Xuesong Huang, Lisha Zeng, Jinzhong Wu (Department of Food Science and Engineering, Jinan University,Guangzhou,China,510632);Advance on the polysaccharide of garlic (Allium sativum L.)[J];Guangzhou Food Science and Technology;2004-04
4 YUE Li1,WANG Hui2,HUANG Xue-song3,SHEN Wei-zai1(1.Department of Anatomy,Medical College;2.Department of Microbiology and Immunology,Medical College;3.Department of Food Science and Engineering,Science and Engineering College,Jinan University,Guangzhou 510632,China);The effects of garlic polysaccharide B(GP-B) on the immunological competence of the immunosuppressed mice[J];Journal of Jinan University(Natural Science & Medicine Edition);2009-06
5 Ge Meng(Biochemical Institute of Tianshui Normal University Gansu Tianshui 741001);Extraction Technology of Polysaccharides from Auricularia by Ultrasonic-assisted Enzymetic Methods[J];;2011-26
6 ZHANG Xi-min,YI Yin(1.School of Life Sciences,Guizhou Normal University,Guiyang,Guizhou 550001,China;2.Key Laboratory of Plant Physiology and Development Regulation,Guiyang,Guizhou 550001,China);Content comparision of bio-macromolecule of three garlics in the market[J];Journal of Guizhou Normal University(Natural Sciences);2013-03
7 Zhang Min,Du Wei-na,Bi Hua,Liu Jian (College of Food Engineering and Biotechnology,Tianjin University of Science & Technology,Tianjin 300457,China);Study on Purification Procedure and Molecular Weight of Oligosaccharide in Cangshan Garlic[J];Food and Fermentation Industries;2011-11
8 LIU Jian-tao~1 WANG Shan~2 ZHANG Wei-min~2 SU Wei~1 ZHAO Li~(1.*) (1.School of Life Science,Jiangxi Normal University of Science and Technology,Nanchang 330013,China; 2.Jiangxi Institution of Food Safety and Inspection,Nanchang 330029,China);Review on Research Progress of Bioactive Constituents in Allium Species[J];Food Science;2007-04
9 LU Wei1,2,ZENG Zhe-ling1,2,DAI Zhi-kai1,2,HAO Chun-qing1,2 (1. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China; 2. College of Life Science and Food Engineering, Nanchang University, Nanchang 330031, China);Extraction and Structural Analysis of Garlic Polysaccharide[J];Food Science;2009-18
10 Cheong Kit Leong,XIE Shun-xin,HUANG Xue-song(Department of Food Science and Engineering,Jinan University,Guangzhou 510632,China);Enzymologic Characteristics of Garlic Fructan Exohydrolase[J];Food Science;2010-11
China Proceedings of conference Full-text Database 1 Hits
1 Cheong Kit Leong, XIE Shun-xin, HUANG Xue-song* (Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China);Some Enzymologic Characteristics of Garlic Fructan Exohydrolase[A];[C];2009
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Hua PENG, Ya-Li LIU, Xiao-Hua HU, Wen LIN, Bing MENG, Li-Min CHEN. Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Role of extracellular signal-regulated kinase signal transduction pathway in viral myocarditis[J];The Chinese Journal of Contemporary Pediatrics;2004-04
2 Ding Jijing, Zhang Tonghua, Sheng Qian (Department of Cardiovasology, Changhai Hospital 200433);The Protective Effect of Astragalus saponins on Coxsackie B, Virus Infected New Born Rat Myocardiac Cells in Culture[J];Academic Journal of Second Military Medical University;1992-06
3 Lu Junhua, Iu Yanqing, Liu Jianjun, et al (Department of Pharmacology, Medical College, Jinan University, Guangzhou 510632);The Cardiac Protective Effects of Qiguihua Ningxin Granules[J];Chinese Journal of Control of Endemic Disenaces;2001-04
4 ZHANG Shu-qin,SUN Fei,LIU Zhi-yi,et al(The regenerate medicine science institute,JiLin university,changchun 132001);Study on antiviral effect of Chan-gan mixture on CoxB_3[J];Chinese Journal of Control of Endemic Diseases;2006-02
5 ZHU Li-an, GUAN Rui-jin, HU Xi-zhong (Fujian Province Cardiovascular Insitute, Fuzhou\ 350001, China)\;;A Model of Viral Myocarditis: Coxsackie B_(3m) Virus Infection in Rat Myocytes[J];JOURNAL OF FUJIAN MEDICAL UNIVERSITY;2000-03
6 Zha Guoqing,et al. (Department of Forensic Pathology, Sun Yat－ sen University of Medical Sciences, Gungzhou 510080);Experimental study on basic fibroblast growth factors in viral myocarditis[J];Journal of Forersic Medicine;2000-04
7 Cheng Jianding, et al. (Department of Forensic Pathology, Sun Yat－ sen University of Medical Sciences, Guangzhou,Guangdong 510080);Histopathological observation of experimental slight viral myocarditis[J];Journal of Forersic Medicine;2001-01
8 Cheng Jianding, Chen Yuchuan, Hu Bingjie (Department of Forensic Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou 510089, P.R.China);Immunohistochemical observation of actin in viral myocarditis[J];JOURNAL OF FORERSIC MEDICINE;1999-02
9 Long Guanzhou;Ouyang Zhi;Li Zhaoji(The Second Affiliated Hospital of Guangzhou Medical College);THE DIAGNOSTIC SIGNIFICANCE OF CARDIAC BLOOD POOL IMAGE OF THE CARDIAC GATE CIRCUIT IN VIRAL MYOCARDITIS[J];JOURNAL OF GUANGDONG MIDICAL COLLEGE;1995-01
10 Guo Shufang, Lu Deyin, Chen Xiao, et al (Virus Research Institute, Basic Medical College, Hubei Medical University, Wuhan 430071, China);Establishment of Method for Detection of Coxsickievirus B IgM Antibody by Reverse indirect ELISA[J];JOURNAL OF HUBEI MEDICAL UNIVERSITY;1998-02
China Proceedings of conference Full-text Database 1 Hits
1 Xuxin,Changchun university of TCM,130117,Jilin,Changchun;The Effect of Qidongyixin Oral Liquid on Viral myocarditis with CVB_3 in mice[A];[C];2010
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Zhang Buchang;Wu Dongru;Tao Leping(Department of Biology Anhui University);Isolation,Purification and Some Properties of Polysaccharides from Asparagus Cochinchinensis[J];JOURNAL OF ANHUI UNIVERSITY(NATURAL SCIENCES);1994-02
2 Wang Xuefeng et al (Dept.of Biology, Suzhou University,Suzhou 215151);Purification and Characterization of Superoxide Dismutase from Garlic[J];Journal of Anhui Agricultural Sciences;2001-03
3 Jin Guangming et al (Department of Animal Science, Anhui technical Teachers College, Fengyang 233100);The Immune Responses of Porcine Reproductive and Respiratory Syndrome(PRRS)[J];Journal of Anhui Agricultural Sciences;2003-01
4 ZHAO Jiang-tao et al(Jiangsu Academy of Agricultural Sciences,Nanjing,Jiangsu 210014);Research on the Role of the Soluble Sugar in the Regulation of Physiological Metabolism in Higher Plant[J];Journal of Anhui Agricultural Sciences;2006-24
5 DONG Yu-ying et al(Department of Environmental Engineering,Dalian Nationalities University,Dalian,Liaoning 116600);Environmental Trend,Harm and Prevention of Antibiotics in the Stockbreeding[J];Journal of Anhui Agricultural Sciences;2008-06
6 LI Dan et al(Navy Medical Institute,Shanghai 200433);Study on Antioxidation Action of Grape Juice[J];Journal of Anhui Agricultural Sciences;2010-03
7 LIU Xue-jing(Center Agricultural Technical Extension of Wulan County,Wulan,Qinghai 817100);Effect of the Different Combinations of N,P and K Fertilizer on the Yield of Garlic Bolt and the Head of Garlic Grown in Qaidam Region[J];Journal of Anhui Agricultural Sciences;2010-26
8 LUO Li et al (College of Grain Oil and Food Science,Henan University of Technology,Zhengzhou,Henan 450052);Structure and Pharmacological Activity of Jujube Polysaccharides[J];Journal of Anhui Agricultural Sciences;2010-30
9 WU Qi-feng et al(Xinjiang Academy of Agri-Reclamation Sciences,Shihezi,Xinjiang 832000);Effect of Different Fertilization and Density on Content of Soluble Sugar of Soybean Seed[J];Journal of Anhui Agricultural Sciences;2012-01
10 ZHENG Chun-yan,WANG Hao-fen,ZHANG Ting-ting*(College of Life Sciences,Anhui Normal University,The Key Laboratory of Biotic Environment and Ecological Safety in Anhui Province,Wuhu 241000,China);Studies on the Anti-Micromial and Anti-Inflammatory Activities of Polygonatum Cyrtonema Hua. Polysaccharides[J];Journal of Anhui Normal University(Natural Science);2010-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 ZENG Qing-hua et al (College of Chemistry and Chemical Engineering,Liaocheng University,Liaocheng,Shandong 202059);Determination of Carbohydrates in Allium sativum L. by High Performance Liquid Chromatography with Evaporative Light Scattering Detection[J];Journal of Anhui Agricultural Sciences;2008-32
2 GONG Hong-dong(Chemistry and Life Science Department,Gansu Normal University for Nationalities,Hezuo,Gansu 747000);Investigation of the Traditional Tibetan Medicine Plant Resources of Allium in the Eastern Area of Qinghai-Tibet Plateau[J];Journal of Anhui Agricultural Sciences;2009-33
3 JI Chun-long et al (College of Chemistry and Life Science,Zhejiang Normal University,Jinhua,Zhejiang 321004);Mycorrhizal Colonization of Onion Seedlings Inoculated with Arbuscular Mycorrhizal Fungi in Different Substrates[J];Journal of Anhui Agricultural Sciences;2010-13
4 LIU Qun et al(College of Life Science and Technology,Southwest University for Nationalities,Chengdu,Sichuan 610041);Effects of Chinese Herbal Compound on the Newcastle Disease Virus[J];Journal of Anhui Agricultural Sciences;2010-20
5 LIANG Si-wen,CHEN Zhen(1.Department of Pharmacology,China Pharmaceutical University;2.Teaching Center of Pharmaceutical and Medical Experiment,China Pharmaceutical University,Nanjing 210009,China);Recent research progress on effect of polysaccharides in enhancing efficacy and reducing toxicity of chemotherapy[J];Anhui Medical and Pharmaceutical Journal;2009-05
6 LI Chang-wen(College of Food and Biology Engineering,Zhengzhou Institute of Light Industry,Zhengzhou,Henan 450002);Study on Comprehensive Utilization and Deep Processing Techniques of Garilic[J];Northern Horticulture;2010-04
7 SUN Xue-mei~1,WANG Li-hui~(1,2),ZHONG Qi-wen~(1,2) (1.Qinghai Academy of Agricuitural and Forestry Sciences,Xining,Qinghai 810016;2.Qinghai Key Laboratory of Heredity and Psychology of Vegetables,Xining,Qinghai 810016);Study on Change of the Carbohydrates Content of Jerusalem artichoke During Storage[J];Northern Horticulture;2011-11
8 WU Yu-fang,QIAO Li-jun,ZHAO Er-lao(Department of Chemistry,Xinzhou Teachers University,Xinzhou Shanxi 034000,China);The Study on Total Phenol and Antioxidant Activities of Garlic Extracts[J];Journal of Jiangxi Normal University(Natural Science Edition);2011-06
9 SUN Ping-ping,WANG Jie,SUN Jian-feng,MU Jian-lou(College of Food Science and Technology,Agricultural University of Hebei,Baoding 071001,China);Optimization of the Polysaccharides Extraction from Razor Clam via Response Surface Method[J];Fisheries Science;2010-04
10 ZHOU Jinghua1,LI Hanwei2,WAN Shunkang1,ZHANG Cuixiang1(1.Pre-clinical College,Dali University,Dali,Yunnan 671000,China; 2.Dali Affiliated Hospital of Dali University,Dali,Yunnan 671000,China);Research Review into the Polysaccharide Structure and Biological Activity of Garlic[J];Journal of Dali University;2010-12
China Proceedings of conference Full-text Database 3 Hits
1 Cheong Kit Leong, XIE Shun-xin, HUANG Xue-song* (Department of Food Science and Engineering, Jinan University, Guangzhou 510632, China);Some Enzymologic Characteristics of Garlic Fructan Exohydrolase[A];[C];2009
2 HUANG Xue-song YANG Jing (Department of Food Science and Engineering,Jinan University,Guangzhou,Guangdong,510632,China);Synthesis and identification of octenylsuccinic garlic polysaccharide[A];[C];2008
3 KONG Xiang-zhi HUANG Xue-song (Department of Food Science and Engineering,Jinan University,Guangzhou,Guangdong,China,510632);Effect of modified pH before or after macroresin column on the garlic polysaccharide and alliinase[A];[C];2008
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved