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《Medical Journal of Wuhan University》 2006-03
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Improved Method and Growth Features of VX_2 Carcinoma in Rabbit Liver

LIU Jun,LIU Zhisu,AI Zhongli,HE Yueming,TANG Shengli,HU JunDept.of General Surgery,Zhongnan Hospital of Wuhan University,Wuhan 430071,China  
Objective: To explore an improved method of establishing rabbit VX_(2) liver tumor transplanting model,and to analyze the characteristics of tumor growth.Methods: Thirty New Zealand white rabbits were divided into three groups at random,with ten in each group.A piece of tumor tissue was implanted into the liver,and the volume of tumor in different periods(by ultrasonography),growth rate of tumor,biological features(histopathology) and the CT scaning of tumor were recorded and analyzed.Results: The tumors grew rapidly in 2-3 weeks,which suggested that the tumor-loaded time of models should be less than four weeks in order to keep neoplasm necrosis and diversion away from influencing experimental results.Conclusion: The improved method of establishing rabbit VX_(2) liver tumor transplanted model is a reliable way to establish rabbit VX_(2) liver tumor transplanted model.
【Fund】: 国家自然科学基金资助项目(编号:30471689)
【CateGory Index】: R735.7
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