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《Medical Journal of Wuhan University》 2008-03
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Progress in Study on Regulator of Aquaporins

CHENG Dongliang,WANG ZhiweiDept.of Thoracic and Cardiovascular Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China  
Aquaporins(AQPs) are a family of integral membrane proteins that selectively transport water.Thirteen mammalian AQPs have been molecularly identified and localized to various epithelial,endothelial and other tissues.Phenotype studies of animals,and in some cases humans with AQPs mutations have demonstrated essential roles for AQPs in mammalian physiology and pathophysiology,including urinary concentrating function,exocrine glandular fluid secretion,brain edema formation,regulation of intracranial and intraocular pressure,skin hydration,fat metabolism,tumor angiogenesis,cell migration and so on.These studies suggest that AQPs regulators may play an important role in some diseases.Potential regulators target for not only new diuretic reagents for various forms of pathological water retention,but also target for novel therapeutic ways of brain edema,inflammatory disease,glaucoma,obesity,and cancer.However,potent AQPs regulators for in vivo application remain to be discovered.
【CateGory Index】: R341
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【References】
Chinese Journal Full-text Database 1 Hits
1 CHENG Dongliang1,2,WANG Zhiwei1,LIU Ping3,WU Hongbing1,GAO Shangzhi11Dep.of Cardiovascular Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China2Dept.of Cardio-Thoracic Surgery,3Dept.of Pathology,Taihe Hospital of Yunyang Medical College,Shiyan 442000,China;Expression of Aquaporin-1 During Acute Myocardium Ischemical Reperfusion Injury in Rats[J];Medical Journal of Wuhan University;2009-05
【Citations】
Chinese Journal Full-text Database 4 Hits
1 FENG Xue-Chao, MA Tong-Hui**(Membrane Channel Research Laboratory, Northeast Normal University, Changchun 130024, China);Physiological Importance of Aquaporin Water Channels Accessed by Phenotype Studies of Aquaporin Knockout Mice[J];Progress In Biochemistry and Biophysics;2005-04
2 XIANG Yang, MA Bing, LI Tao,YU He-Ming, LI Xue-JunDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100083; National Research Institute for Family Planning, Beijing 100081, China;Acetazolamide suppresses tumor metastasis and related protein expression in mice bearing Lewis lung carcinoma[J];中国药理学报(英文版);2002-08
3 Bing MA, Yang XIANG, Tao LI, He-ming YU, Xue-jun LIDepartment of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100083; National Research Institute for Family Planning, Beijing 100081, China;Inhibitory effect of topiramate on Lewis lung carcinoma metastasis and its relation with AQP1 water channel[J];中国药理学报(英文版);2004-01
4 LI Yanhua, SUN Shanquan. Department of N eurobiology, Chongqing University of Medical Science, Chongqing 400016, China;Expression of aquaporin4 protein in brain from rats with hemorrhagic edema[J];Chinese Critical Care Medicine;2003-09
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Yanbin, LU Zhi, GUO Guiming. Department of Orthopedics, The Second Hospital of Shanxi Medical University,Shanxi, 030001, China;The expression of aquaporin 1 in osteosarcoma and its significance[J];Chinese Journal of Bone Tumor and Bone Disease;2008-03
2 JIANG Jiao-de,MA Zhi-ming,LIU Yu-sheng(Department of Neurosurgery,Xiangya Hospital,Central South University,Changsha 410008,China);Expression of aquaporin-4 protein in rats with acute radiation-induced cerebral edema[J];Journal of Central South University(Medical Sciences);2008-03
3 YANG Huifeng,YUAN Weitang The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Expression and Significance of Aquaporin 3 and Aquaporin 9 in Colonic Mucosa[J];Journal of Medical Forum;2007-06
4 MENG Lan-qing,HUANG Rui-ya,ZHU Cheng-liang,et al (Department of Neurology,Affiliated Hospital of Youjiang Medical College,Baise 533000,China);The effect of PNS on expression of AQP4 and brain edema after intracerebral hemorrhage in rats[J];Chinese Journal of Geriatric Heart Brain and Vessel Diseases;2007-01
5 LOU Qin, WANG Qin, LUO Zhihong. Department of Library, The First Affiliated Hospital, Chongqing of Medical University Chongqing 400016;Metrological analysis of literature on diabetes insipidus reported during the period 1994~2006 in China[J];Journal of Endocrine Surgery;2007-03
6 LIU Jin-yuan,ZHANG Shi-jiang,JIN Yu1,WANG Mei1,XIE Wei-ping1,WANG Hong1 (Department of Thoracocardiac Surgery,1Department of Respiratory Medcine,the First Affiliated Hospital of NJMU,Nanjing 210029,China);Expression and distribution of aquaporin 1 in the adenocarcinoma of lung[J];Acta Universitatis Medicinalis Nanjing(Natural Science);2008-04
7 Jing Li, Chang-Qing LiDepartment of Neurology, the Second Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400010, China;Edema in the Surrounding Tissues of Cerebral Hematoma After Intracerebral Hemorrhage[J];Cerebrovascular Diseases Foreign Medical Sciences;2005-12
8 LIN Gui-ping,XIANG Qiu-ling,CHEN Jian-wen,MA Ren-qiang,TANG Min-yi,XIE Dai-xi(Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080,China);Protective Effects of Peoniflorin on Cerebral Ischemia Injury and Its Effects to Cerebral Vessels Permeability[J];Journal of Tropical Medicine;2009-02
9 LIU Jun, SHI Lin-Lin, YANG Hong, MA Tong-Hui**(Membrane Channel Research Laboratory,Northeast Normal University, Changchun 130024, China);Water Channels on The Move: a New Focus on Mechanisms of Cell Migration and Related Biological Processes*[J];Progress In Biochemistry and Biophysics;2005-07
10 Xiao Liang,Yang Zhen,Li Dong-Jian,et al Department of Surgery,Tongji Hospital,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030;Aquaporin-4 on Vascular Permeability in Encephalopathy of Schistosomiasis[J];Chinese Journal of Microcirculation;2006-04
China Proceedings of conference Full-text Database 1 Hits
1 GUO Hao LI Xue-jun Department of Pharmacology,School of Basic Medical Sciences and State Key Laboratory of Natural & Biomimetic Drugs,Peking University,Beijing 100083,P.R.China.;Aquaporin 1 is Involved in the Antimigration Effect Of 20(R)-Ginsenoside Rg3[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 XIA Ying △ ,CHEN Xian cheng,JI Yao dong,REN Hui min,FU Rong,GONG Ye ( △ Department of Neurosurgery,Jinshan Hospital,Fudan University,Shanghai 200540; Department of Neurosurgery,Huashan Hospital,Fudan University,Shanghai 200040);Relationship between Brain Edema Formation after Intracerebral Hemorrhage and Effects of Glucose Metabolic Alteration,Free Radical Release and Blood-Brain Barrier Permeability[J];Journal of Shanghai Medica(University);2002-02
2 XU Zhiqiang,CHEN Mane,JIANG Xiaojiang,WANG Jingzhou.Third Department of Neurology,Daping Hospital,Third Military Medical University,Chongqing 400042;Changes in noradrenaline in perihemotoma brain tissue and hypothalamus in rats with intracerebral hemorrhage[J];Chinese Critical Care Medicine;2002-01
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