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《Journal of Hebei Medical University》 1992-01
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Li Yongfang Wang Yukun Gu Baoliang Department of Microbiology  
In propagation of human rotaviruses (HRV) and induction of typical cytopathic effects (CPE) of infected cells, trypsin treatment and roller culture technics were of crucial importance During cloning a virus mixture mixed by HRV FH4232 with Simian Rotavirus SA11, two reassortants of FH4232 and SAll were obtained. From analysis on viral RNA, it was found that the 5th and 11th segments of reassortant RNA electropherotype were stemed from parental RNA of strain FH4232, and the others from SA11. Rotavirus reassortants generated in vitro might account for the variability of HRV in vivo. In addition, these human-animal rotavirus reassortants would be offered to promise as potential vaccine candidates.
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Chinese Journal Full-text Database 1 Hits
1 CHEN Jun-hua1,XIE Yuan-yuan1,LING Hua2,LIU Zuo-yi1(Department of Infection and Gastroenterology,Children's Hospital,Chongqing Medical University,Chongqing 400014;Chongqing Center for Disease Control and Prevention,Chongqing 400042,China);On pathogenesis of rotavirus diarrhea in suckling mouse[J];Acta Academiae Medicinae Militaris Tertiae;2007-12
Chinese Journal Full-text Database 10 Hits
1 YAO Ying-min1, OU Qiao-qun1, CHEN Yao2 Department of Pediatrics, Nanfang Hospital1, School of Biotechnology2, Southern Medical University, Guangzhou 510515, China;Ultrastructural changes of the extraintestinal organs of newborn mice with human rotavirus infection[J];Journal of Southern Medical University;2006-09
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 CHEN Jun-hua,XIE Yuan-yuan,ZHU Chao-min,LIU Zuo-yi(Department of Infectious Disease,Children's Hospital,Chongqing Medical University,Chongqing 400014,China);Extraintestinal lesions caused by rotavirus:An experimental study on suckling mice[J];Acta Academiae Medicinae Militaris Tertiae;2009-15
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