Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Harbin Medical Journal》 2011-01
Add to Favorite Get Latest Update

Protective Effect of Flavonoids from Ampelopsis Grossedentata on Immunological Liver Injury in Mice

OU Xianhong1,ZHENG Zuowen2(1.Guilin Medical University,Guilin 541004,China;2.Guangxi Traditional Chinese Medical University,Nanning 530001,China)  
Objective To investigate the effect of Tengcha flavonoids(TF) on immunological liver injury induced by BCG plus LPS in mice.Methods BCG plus LPS were used to produce immunological liver injury model in mice.Serum hepatic function indexes,such as ALT,AST,MDA and SOD were measure.Liver tissues were dyed with HE and histopathological changes in liver were observed under light microscope.Results TF inhibited significantly the increase of ALT,AST and MDA in serum while SOD was increased.Histopathological changes were improved.Conclusion TF showed significant protective action on immunological liver injury in mice,and the effect on depression the oxygenation of free radicle maybe its one of protection liver mechanisms.
【CateGory Index】: R285.5
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 1 Hits
1 WANG Hua,WEI Wei, YUE Li,WANG Ni ping ,GUI Shuang ying,WU Li,SUN Wu yi,XU Shu yun (Institute of Clinical Pharmacology , Anhui Medical University, Hefei 230032,China);Protective effect of total glucosides of paeony on immunological liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide[J];Chinese Pharmacological Bulletin;2004-08
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 Gao Benbo; Dai Liming; Xu Shuyun(Institute of Natural Drugs 261042);THE SCAVENGING ACTIVITIES OF TGM AND TGP ON FREE RADICALS[J];JOURNAL OF WEIFANG MEDICAL COLLEGE;1996-01
2 Wei Wei, Liang Junshan Zhou Aaiwu et al (The clinical Pharmacology Institute, Anhui Medical University, Hefei );EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J];Chinese Pharmacological Bulletin;1989-03
3 DAI Li-Ming, CHEN Xue-Guang, XU Shu-Yun (Dept Of Pharmacology, Anhui Medical University, Hefei, 230032);Protective effects of total glucosides of paeony on experimental hepatitis[J];Chinese Pharmacological Bulletin;1993-06
4 ZHOU Ling Ling 1, WEI Wei, SHEN Yu Xian, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032) 1Dept of Pharmacology,Nanjing University of Traditional Chinese Medicine,Nanjing 210029;The effects of TGP on CJ-S_(131)-induced systemic lupus erythematosus-like model in mice[J];Chinese Pharmacological Bulletin;2002-02
5 GE Zhi-Dong; ZHOU Ai-Wu; WANG Bin et al(Institute of Clinical Pharmacology,Anhui Medical University,Hefei 230032 );Immunoregulatory effects of total glucosides of paeony (TGP),paeoniflorin (PF) and TGP removed PF on adjuvant arthritic rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1995-04
6 WANG Bin, CHEN Min Zhu, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);Regulatory mechanism of total glucosides of paeony on tumor necrosis factor production by peritoneal macrophages in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1997-03
7 XU Shu-Yun;SHEN Yu-Xian;XU Du-Juan;WEI Wei;LIANG Jun-Shan(Institute of Clinical Pharmacology,Anhui Medical University),Hefei 230032;Effects of total glucosides of paeony and moutan cortex on the fonctions of pineal gland in inflammatory-immune regulation in rats[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;1994-03
8 WANG Bin, YAO Yu You, ZHOU Ai Wu, GE Zhi Dong, CHEN Min Zhu, XU Shu Yun (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);Protective effect of total glucosides of paeony on joint damage in adjuvant arthritis rats[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;1996-03
9 Wang Bin; Yao Yuyou; Zhou Aiwu et al. (Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032);STUDY ON IMMUNOMODULATORY EFFECT OF TOTAL GLUCOSIDES OF PAEONY AND ITS RELATIONSHIP WITH NITRIC OXIDE IN ADJUVANTARTHRITS RATS[J];CHINESE JOURNAL OF IMMUNOLOGY;1996-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved