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《Harbin Medical Journal》 2011-01
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New Generation of Angiotensin Converting Enzyme Inhibitors,Fosinopril

GAO Yonggui,YANG Jun,ZHANG Chunjuan(Dongli Hospital of Traditional Chinese Medicine in Tianjin,Tianjin 300300,China)  
Fosinopril is the third generation of containing phosphonate angiotensin converting enzyme inhibitors(ACEI),through specific inhibition of the angiotensin converting enzyme peripheral vascular and organization of peripheral vascular and organization the angiotensin converting enzyme way of blocking angiotensin Ⅱ synthesis,and inhibits enzymes that induced too slowly,promoting peptide degradation of vascular endothelial release shu,step-down effect-acting slowly and gradually increase,the maximum effect in near,sodium salt limited or using diuretics can make the effect-acting quickly and enhancement.Fosinopril blessed with improvement of insulin resistance and lower urinary protein function.In obesity,diabetes,hypertension and kidney organs such as the heart and kidney damage,the primary hypertension patients,Fosinopril can have relatively good curative effect,is especially suitable for the associated with heart failure,myocardial infarction,impaired glucose tolerance,diabetic nephropathy hypertension patients.Its characteristic is less adverse effect,smooth effect,no orthostatic hypotension,etc.
【CateGory Index】: R972
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【Citations】
Chinese Journal Full-text Database 1 Hits
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【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 ZHOU Shi-li,WANG Jian-gang (Department of Cardiovascular Diseases,Beiya Hospital,Zhuzhou,Hunan 412000,China);Antihypertensive Efficacy and Effect of Combined Therapy With Telmisartan and Ramipril on Cardiac Function of the Patients With Hypertension[J];Journal of Nanhua University(Medical Edition);2008-05
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3 HUANG Bang-hua,JIANG Xue-hua(West China School of Pharmacy,Sichuan University,Chengdu 610041,China) HUANG Bang-hua,PU Yan-fang,ZHANG Zhi-qing(Dept.of Clinical Pharmacy,Yunnan Provincial First People's Hospital,Kunming 650032,China);Systematic Review of Angiotensin-converting Enzyme Inhibitor Combined with Angiotensin Receptor Blocker in the Treatment of Primary Hypertension[J];China Pharmacy;2010-34
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