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《Hebei Medical Journal》 2011-04
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Experimental study on the therapeutic effect of femoral head plastic operation on aseptic necrosis of femoral head

LIU Zhiguo*,SU Wengang,LI Ying*,et al.*The First Central Hospital of Baoding City,Hebei,Baoding 071000,China  
Objective To observe the preventive and therapeutic effect of femoral head plastic operation on aseptic necrosis of femoral head in rabbits.Methods 60 Chinese white rabbits were randomly divided into 4 groups.Except for the group A(control group),the rabbits in the other three groups were made a globose defect and filled with 95% alcohol tampon for 30 minutes.The group B was natural repair group,and the rabbits in group C were filled with bone cement after being made defect.The rabbits in group D were filled with bone cement plus barium sulfate agent after being made defect.After 12 weeks the rabbits in four groups were killed.The specimens were randomly divided into two parts.The one part's articular cartilages were observed and detected immediately.The other ones were treated by histological examination and extreme anti-pressure rigidity test.Results The femoral heads in bone cement group and the femoral head of contrast agent bone cement group kept their outline all the time identified by the articular cartilage observation.12 weeks later the cartilage thickness of natural repair group was significantly thinner than that of the other three groups(P0.05).The rigidity of natural repair group had significant difference with that of the other three groups respectively(P0.01).Conclusion Femoral head plastic operation is simple and can relieve pain,with little trauma,furthermore,the integrity of femoral head outline can be kept,which may become a new way that is used to treat young patients with aseptic necrosis of femoral head in FicatⅡ~Ⅲ period to substitute total hip replacement.
【CateGory Index】: R681.8
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