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《Hebei Medical Journal》 2011-04
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Experimental study on the therapeutic effect of femoral head plastic operation on aseptic necrosis of femoral head

LIU Zhiguo*,SU Wengang,LI Ying*,et al.*The First Central Hospital of Baoding City,Hebei,Baoding 071000,China  
Objective To observe the preventive and therapeutic effect of femoral head plastic operation on aseptic necrosis of femoral head in rabbits.Methods 60 Chinese white rabbits were randomly divided into 4 groups.Except for the group A(control group),the rabbits in the other three groups were made a globose defect and filled with 95% alcohol tampon for 30 minutes.The group B was natural repair group,and the rabbits in group C were filled with bone cement after being made defect.The rabbits in group D were filled with bone cement plus barium sulfate agent after being made defect.After 12 weeks the rabbits in four groups were killed.The specimens were randomly divided into two parts.The one part's articular cartilages were observed and detected immediately.The other ones were treated by histological examination and extreme anti-pressure rigidity test.Results The femoral heads in bone cement group and the femoral head of contrast agent bone cement group kept their outline all the time identified by the articular cartilage observation.12 weeks later the cartilage thickness of natural repair group was significantly thinner than that of the other three groups(P0.05).The rigidity of natural repair group had significant difference with that of the other three groups respectively(P0.01).Conclusion Femoral head plastic operation is simple and can relieve pain,with little trauma,furthermore,the integrity of femoral head outline can be kept,which may become a new way that is used to treat young patients with aseptic necrosis of femoral head in FicatⅡ~Ⅲ period to substitute total hip replacement.
【CateGory Index】: R681.8
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 KONG Ling-Bo,NIU Shun,YANG Chong-Fei,ZHU Qing-Sheng Institute of Orthopaedics,Fourth Military Medical University,Xi'an 710033,China;Establishment and evaluation of rabbit model of femoral head avascular necrosis[J];Journal of the Fourth Military Medical University;2009-02
2 ZHAO Fengchao, LI Zirong, ZHANG Nianfei, et al. Center for Osteonecrosis and Joint-Preserving & Reconstruction, China-Japan Friendship Hospital, Beijing, 100029, P. R. ChinaCorresponding author:LI Zirong;CALCULATION OF ARTICULAR SURFACE AREA OF OSTEONECROSIS AND ITS APPLICATION IN PREDICTING COLLAPSE OF THE FEMORAL HEAD[J];Chinese Journal of Reparative and Reconstructive Surgery;2005-09
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 HE Wei1, ZENG Qin2, ZHANG Qingwen1, LI Yong1, PANG Zhihui1, ZENG Ping1, WANG Haibin1, YUAN Hao1. 1 Department of Orthopaedics, 1st Affiliated Hospital of Guangzhou Traditional Chinese Medicine University, Guangzhou Guangdong, 510405, P. R. China; 2 Department of Orthopaedics, Dongguan Hospital of Traditional Chinese Medicine.;STUDY ON CORRELATION BETWEEN PAIN GRADING, STAGE OF NECROSIS AND BONE MARROW EDEMA IN NONTRAUMATIC OSTEONECROSIS OF FEMORAL HEAD[J];Chinese Journal of Reparative and Reconstructive Surgery;2008-03
2 Qi Xin-wen, An Rong-ze, Wang Zhao-jie Department of Orthopedics of the Fifth Affiliated Hospital (Zhuhai Hospital) of Zunyi Medical College, Zhuhai 519100, Guangdong province, China;Expression and significance of bcl-2 and bax genes during the development of traumatic avascular necrosis of the femoral head[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2009-37
3 Liu Zhiguo,Su Mingang,Li Ying,Zhen Yuting,Fu Xing.The First Center Hospital of Baoding,Hebei 071000,China;An Experiment Study on Aseptic Necrosis of the Femoral Head in Rabbits Treated with Femoral Head Plastic Operation[J];Journal of Medical Research;2010-08
【Secondary Citations】
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1 Wang Weiming,Zhao Dewei,Depatrment of Orthopaedics, 4 th Hospital,Dalian Medical University,Dalin,116001;An Experimental Research of Refrigeration with Liquid Nitrogen to ONFH[J];The Journal of Bone and Joint Injury;2001-06
2 YANG Shu hua,YANG Cao,XU Wei hua,et al.Department of Orthopedics,Union Hospital,Tongji Medical University.Wuhan,430022;Avascular Necrosis of the Femoral Head Produced in Rabbits by Freezing[J];The Orthopedic Journal of China;2001-01
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