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《HEBEI MEDICINE》 2000-04
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Diagnostic value of serum CA-50 measurement in patients with carcinoma of digestive system

WT4”BX]GAO Zhong du,YUAN Wei xiang,MAO Ai wu,WANG Min,JIANG Ting hui [WT4”HX](Shanghai Tongren Hospital ,Shanghai 200050, China) [WT5HZ]  
Objective :[WT5BZ][ST5BZ]To evaluate the diagnostic value of contents of serum and asocitic CA 50 in the cases with carcinomatous ascites.[WT5HZ]Methods:[WT5BZ]The serum CA 50 content was measured by radioimmunoassay in 54 normal individuals,176 patients with carcinoma of digestive system and 160 patients with benign diseases.[WT5HZ]Results:[WT5BZ] The normal value was 3.80+2.45Ku/L,The content of serum CA 50 in patients with carcinoma were much higher than those of healthy people and patients with benign diseases(P0.001 in both),and this occurred in the early stage and became even more obvious in the late stage.Taking the normal mean value plus two times of standard deviation as positive,the positive rate was 85.8% for carcinoma of digestive system.There was only two positive in 52 normals with a fale positive rate of 3.7%.[WT5HZ]Conclusion: [WT5BZ]The detection of both serum CA 50 and ascitic CA 50 may have a certain clinical prectical value in carcinoma of the digestive system diagnosis,differential diagnosis and the monitor,prediction of prognosis. [WT5HZ]
【CateGory Index】: R730.5
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