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《Entomological Journal of East China》 2007-02
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Progress in molecular mechanisms of insect resistance to insecticides

KANG Chun-yu1,3,ZHAO Chun-qing2,WU Gang3(1.College of Food Science and Technology,Hebei Agriculture University,Baoding,Hebei 071001,China;2.Hebei Radio and TV University,Baoding,Hebei 071000,China;3.Key Laboratory of Biopesticide and Chemical Biology,Ministry of Education,(Fujian Agriculture and Forestry University),Fuzhou,Fujian 350002,China)  
Researching on mechanisms of insect resistance is very importance to develop effective strategies for detecting,monitoring insect resistance and new pesticide research.In the past years, a great deal of study on insect's insecticide resistance-related mechanisms,such as behavior,physiological function,metabolism and target-site,was reported.Its has been proven correct that mechanisms of insect resistance were conferred by changed behavior,modified physiological function,enhanced detoxification and reduced target sensitivity.Recently,with the development of the molecular biology and insect genomes,the molecular mechanism of insect resistance has been elucidated to a great degree.Some target genes have been identified and cloned in many insects.Some insecticide resistance related mutations have been examined in some insects.This paper reviewed the progress in molecular mechanisms of insect resistance to insecticides.The changes in genes related to insecticide resistance include amplification,over expression and structure change were introduced in detail.
【Fund】: 科技部资助项目(05DFA30440);; 福建省科技厅资助项目(05I002)
【CateGory Index】: S433
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