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《Chemical Industry and Engineering Progress》 2007-06
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Study on the synthesis and performance of caffeine molecularly imprinted polymer micro-spheres via precipitation polymerization

YAO Wei,GAO Zhixian,FANG Yanjun,CHENG Yiyong(Institute of Hygiene and Environmental Medical Sciences,Academy of Military Medical Sciences,Tianjin 300050,China)  
Molecularly imprinted polymers(MIPs) were prepared via precipitation,with methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the cross-linker in acetonitrile solution using caffeine as the template molecule and 2,2′-azobis-isobutyronitrile as the initiator.The effects of the amount of cross-linker,functional monomer,initiator,the volume of solvent were examined.Equilibrium binding experiments was used to investigate the binding ability to template molecule,and the results revealed that the MIPs showed specific binding affinity to caffeine.
【Fund】: 国家科技支撑计划(No.200BAK02A09);; 天津市自然科学基金(No.06YFJMJC07700)资助项目
【CateGory Index】: TQ316.33
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