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《Nuclear Techniques》 2001-11
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Measurement of portal vein pressure by ~(99m)Tc-MIBI for the evaluation of the staging and therapeutic effect in cirrhosis

SU Chenghai BI Peiying JIANG Yimin WU Yiwei ZHANG Wei DONG Shen'an SANG Shibiao CHEN Weichang XU Fengpo WU Xinghong (The First Affiliated Hospital, Suzhou University, Suzhou 215006)  
The heart/liver ratio (H/L) and portal vein pressure (PVP) in 54 patients of cirrhosis with various liver function were determined by the rectal administration of 99m Tc-MIBI, The H/L ratio in Child A (21 cases), Child B (15 cases) and Child C (18 cases) group was 0.49±0.18, 0.69±16 and 0.91±0.21 respectively, whereas the PVP was 2.22±0.57kPa, 2.85±0.38kPa and 3.54±0.65kPa respectively. In normal controls (16 cases), the H/L ratio and PVP was 0.30±0.12 and 1.61±0.38kPa. There was no significant difference in PVP between Child B and C groups, but has very significant ( P 0.001) and significant ( P 0.05) difference of H/L ratio and PVP in remaining groups after t test. In 16 cirrhotic patients the H/L ratio and PVP was 0.73±0.16 and 3.00±0.55 before treatment, and become 0.47±0.18 and 2.20±0.62kPa after treatment, there was also very significant difference after t-test. It was concluded that this method for the determination of PVP is not only convenient, but also atraumatic and acceptable for the patient. Thereby, it has unique value for the staging, monitoring therapeutic effect, guiding treatment protocol and jndging the prognosis etc. in cirrhotic patients.
【CateGory Index】: R817.4
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