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《Environmental Pollution & Control》 2002-02
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Study on DNA damage of spermary cell in mice induced by environmental endocrine disrupting chemicals

Kong Zhiming , Zhang Guodong, Sun Liwei, et al. State Key Laboratory of Pollution Control and Resource Rease, Environmental School, Nanjing University, Nanjing 210093  
The single cell gel electrophoresis technique (SCGE) was used to detecte the DNA damage of spermary cell in mice, which were induced by 9 tested environmental endocrine disrupting chemicals. The results show that all the nine tested substances can induce different levels DNA damages, and the dose response relation were obvious. The high dose group and the control group were significantly different (P0.01). It is also showed that the degree of DNA damages were partly related to the structure of alkyl hydroxybenzene compound.
【Fund】: 国家自然科学基金资助项目 (No.2 99770 2 0 )
【CateGory Index】: R394.6
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