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《Environmental Pollution & Control》 2004-03
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Study progress on molecular toxicity mechanism of the environmental pollutant

Lu Yitong Zhu Jiang Yu Jiali(Agriculture Environmental Ecological Institute, Shanghai Jiaotong University, Shanghai 201101)  
With the development of the theory and technique of modern biology, especially the molecular biology, many new techniques were employed in the research of environment. Mechanisms of toxicological effect of environmental pollutant on organisms were illustrated from the DNA levels. The domestic and international research progress of molecular toxicity mechanism of the environmental pollutant was reviewed. In the paper, characteristics, problems and future development of molecular biology technology such as: toxchip, single cell gel electrophoresis, etc.while studying in toxicology were summarized in detail, the aspect which need to be further studied were also suggested.
【Fund】: 国家自然科学基金资助项目 ( No.2 0 3 3 70 10 )
【CateGory Index】: X50
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Chinese Journal Full-text Database 4 Hits
1 LIU Yao ZHOU Qi-xing(Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education),College of Environmental Science and Engineering,Nankai University,Tianjin,300071,China);RESEARCHING ADVANCES AND PROSPECTS IN MOLECULAR DIAGNOSIS OF WATER AND SOIL-ENVIRONMENTAL CONTAMINATION[J];Environmental Chemistry;2010-04
2 HU Shan-shan~1,SHEN Xiu-ying~1,XU Xiao-lu~2(1.College of Chemistry and Life Sciences,Zhejiang Normal University,Zhejiang Jinhua 321004 PRC;2.Shaoxing College of Arts and Sciences,Zhejiang Shaoxing 312000 PRC);Summary on the Toxicological Effect and Mechanism of Bisphonel A[J];Jiangxi Science;2006-05
3 XU Chang-jun,MAN Long-sheng,YIN Ya-jie,QIN Shu-mian,ZHANG Hong,BIAN Li-hong(School of Life Sciences,Daqing Normal College,Daqing 163712,Heilongjiang,China);Study on DNA Damages of Limnodrilus hoffmeisteri by Water from Longfeng Wetland[J];Hubei Agricultural Sciences;2013-14
4 ZHOU Chi1,2,LI Chun-hou1(1.South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Guangzhou 510300,China;2.Shanghai Fisheries University,Shanghai 200090,China);Macromolecule biomarker detection used in environmental monitoring[J];Journal of Fishery Sciences of China;2007-05
Chinese Journal Full-text Database 7 Hits
1 ZHUANG Zhi\|Xiong (Shenzhen Health and Anti\|epidemic Station 518020);Application of new technology on cellular and molecular biology to toxicological research in China[J];JOURNAL OF HEALTH TOXICOLOGY;1999-04
2 HU Wen Wei, YU Ying Nian, CHEN Xing Ruo, XIE Hai Yang (Department of Pathophysiology, School of Medicine, Zhejiang University, Hangzhou 310031, China);Construction of the eukaryotic expression plasmid compatible with the detection system of shuttle plasmid pZ189[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;2000-02
3 CAO Jia1,ZHOU Zi- Yuan1,FANG Fu- De2 ,YANG Meng- Su3,HU Shao- Shen3,YOU Li4 (1 .Molecular Toxicology Laboratory,the Third Military Medical University,Chongqing 40 0 0 38,China; 2 .The Key National Laboratory of Medical Molecular Biology,Institute of B;Toxicogenomics and applications of DNA microarrays[J];CHINESE JOURNAL OF PHARMACOLOGY AND TOXICOLOGY;2000-05
4 SHAO Hua,SHI Yi kang.Shandong Institute of Labor Health and Occupational Disease(Jinan 250062,China);Determination of adduct actions of mixed pesticides on DNA by ultraviolet spectral method[J];China Public Health;2003-01
5 ZHOU Li,ZHANG Yixi,SHI Nian.Department of Toxicology,Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China;Comparison of the toxic effect of methamidophos and acephate on acetylcholinesterase[J];Chinese Journal of Indusreial Hygiene and Dccupational Diseases;2002-06
7 Xu Lihong (Institute of Hydrobiology, CAS, Wuhan 430072);THE STUDY OF DNA ADDUCTS AND ITS APPLICATION IN ENVIRONMENTAL TOXICOLOGY[J];Bulletin of National Science Foundation of China;1999-05
Chinese Journal Full-text Database 10 Hits
1 WANG Guo-fu et al(Department of Life Sciences,School of Yuanpei,,Shaoxing University of Arts and Sciences,Shaoxing,Zhejiang 312000);Comparison of Antifeedant Activity of Extracts from Three Plants to Pieris rapae[J];Journal of Anhui Agricultural Sciences;2010-15
2 WANG Guo-fu,ZHONG Jun-yan,HU Chun-xia (Department of Life Science,Shaoxing University Yuanpen College,Shaoxing Zhejiang.312000);Extraction of Active Ingredients in Xanthium Sibiricum Patrin and Analysis of Its Insecticidal Activity[J];Northern Horticulture;2010-03
3 Sun Deli,Shu Qijin△ Zhejiang College of TCM,Hangzhou(310053)△Zheijiang Provincial Hospital of TCM;Gene Expression Profile-Thinking of TCM Functional Genomics Research[J];Journal of Zhejiang College of Tcm;2002-01
4 ZHENG Wei-hua, ZHAO Jian-zhuang (Beijing Agricultural College, Beijing 102206);Development of Deltamethrin Toxicity and Mutagenicity[J];Journal of Beijing Agricultural College;2004-01
5 Chen Yong et al (Hubei University);Study on Gene Chip Technology of Evaluation of Hepatotoxicity of Chmese Medicines[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-06
6 ZHANG Hong ying,CHI Guo tong,ZHANG Jin lin (College of Plant Protection, Agricultural University of Hebei, Baoding 071001, China);The progress of detoxification enzyme systems and resistance of insecticide[J];Journal of Agricultural University of Hebei;2002-S1
7 ;Enhancing the study of environmental carcinogenesis, teratogenesis and mutagenesis[J];Acta Academiae Medicinae Militaris Tertiae;2003-19
8 ;Toxicogenomics: A new field in toxicology[J];Acta Academiae Medicinae Militaris Tertiae;2005-19
9 HUANG Liang-liang1,WU Zhi-qiang1,2,HU Mao-lin2 (1.School of Life Science,Nanchang University,Nanchang 330031 2.The Key Lab of Poyang Lake Ecology and Bio-resource Utilization,Ministry of Education,Nanchang 330047);Effects of Acephate on Brain Acetyl Cholinesterase in Carassius auratus[J];Freshwater Fisheries;2007-05
10 LI Yi-qiang1, 2, CHANG Wei-min2, SUN Li-wei1, QU Meng-meng1, KONG Zhi-ming1, GUO Xiao-ying2, SHEN Yan-fei2 (1.State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210093; 2.Environment Monitoring Center of Jiangsu Province, Nanjing 210036);Application of Fish Micronucleus Test on the Environmental Protection Acceptance Monitoring at Project Completion[J];Environmental Science & Technology;2006-02
China Proceedings of conference Full-text Database 1 Hits
1 LIU Wei, ZHU Lu-sheng, WANG Jun, XIE Hui , SONG Yan ,WANG Xiu-guo, WANG Qian, QIAN Bo (College of Resources and Environment, Shandong Agricultural University, Tai An 271018, China);Determination of the Damage of Three Pesticides on DNA by Absorption Spectrophotometry and Micronucleus Test[A];[C];2005
Chinese Journal Full-text Database 10 Hits
1 ZHANG Zun-zhen, HENG Zheng-chang, LIAO Yan, ZHAO Rong (Department of Environment Health, West China University of Medical Sciences, Chengdu 610041,China);STUDY ON DNA DAMAGE INDUCED BY INDIRECT MUTAGENS USING COMET ASSAY IN TESTICULAR CELLS IN VITRO[J];Carcinogenesis,Teratogenesis and Mutagenesis;2001-01
2 CAO Yi, CHEN Rui, WANG Zhong_wen, et al(China Institute for Radiation Protection,Taiyuan 030006, China);MEASUREMENT OF DNA DAMAGES INDUCED BY RADIATION AND CHEMICALS USING COMET ASSAY[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-03
3 JIN Long_jin,LOU Zhe_feng,DONG Jie_ying,et al (Central Laboratory of Biology,Wenzhou Medical Collage,Wenzhou325027,China);Effects of Cadmium and Mercury on DNA Damage of Mice Bone Marrow Cell and Testicle Germ Cell in vitro[J];Carcinogenesis,Teratogenesis and Mutagenesis;2004-02
4 Ma Aiguo 1,Andrew R.Collins 2,Susan J.Duthie 2 1Department of Human Nutrition,Qingdao Medical College,Qingdao 266021, 2The Rowett Research Institute,U.K.;THE DIFFERENCES OF DNA DAMAGE AND REPAIR BETWEEN SEVERAL TYPES OF CELLS[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1997-03
5 LI Yun-ling et al(College of Life Science,Ludong University,Yantai,Shandong 264025);Proliferation Characteristic of Mantle Cells of the Clam Ruditapes philippinarum in Vitro Culture[J];Journal of Anhui Agricultural Sciences;2007-05
6 LIU Hai-fang et al(School of Energy & Environmental Engineering,Zhongyuan University of Technology,Zhengzhou,Henan 450007);Progress of Research on Molecular Biomarkers for Monitoring Contamination Level of Water System[J];Journal of Anhui Agricultural Sciences;2007-18
7 LIN Ai-wei et al(College of Life Sciences,South China Normal University,Guangzhou,Guangdong 510631);Acute Toxicity of Mercury,Chrome and Nickel to Tanichthys albonubes and Their Safety Assessment[J];Journal of Anhui Agricultural Sciences;2009-02
8 HEI Shu-mei(College of Life Science,Yanan University,Yanan,Shaanxi 716000);Effects of Heavy Metal-Chromium on the DNA Methylation in Wheat Seedling[J];Journal of Anhui Agricultural Sciences;2011-13
9 LUO RONGSHENG WANG YOULAN CAO MEIXUN GU ZHIMIN(Shanghai Institute of Cell Biology, Academia Sinica) Shanghai Institute of Entomology, Academia Sinica, Fresh-water Fisheries Institute of Zhejiang.;THE ROLE OF HEMOLYMPH 20-HYDROXYECDYSONE IN MOLTING AND OOCYTE DEVELOPMENT OF THE CRAB ER1OCHEIR SINENSIS H. MILNE EDWARDS[J];Acta Zoologica Sinica;1990-02
10 SHANGGUAN BU-MIN; LI SHAO-JING (Department of Oceanography, Xiamen University, Fujian 361005 );MICROSTRUCTURAL AND ULTRASTRUCTURAL STUDIES ON THE SINUS GLAND OF SCYLLA SERRATA[J];Acta Zoologica Sinica;1995-04
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 KUANG Hua et al(School of Food Science and Technology,Jiangnan University,Wuxi,Jiangsu 214122);Preparation of Polyclonal Antibody of Anti-bisphenol A[J];Journal of Anhui Agricultural Sciences;2011-34
2 QIN Bei(Xi'an Medical University,Xi'an 710021,China);Progress of Plastic Food Packaging Safety Research[J];Packaging Engineering;2011-19
3 Yan Zhenguang 1,2,Liu Zhengtao 1,2,Meng Wei 1(1.State Key Laboratory of Environmental Criteria and Risk Assessment,Chinese Research Academy of Environmental Sciences,Beijing 100012,China;2.State Environmental Protection Key Laboratory of Ecological Effect and Risk Assessment of Chemical,Chinese Research Academy of Environmental Sciences,Beijing 100012,China);Development of emergency water quality standards for Cr~(6+) and Hg~(2+) in Liaohe River basin[J];Engineering Sciences;2013-03
4 LI Huixian1,2, ZHANG Ruiqing1,2,3,4, WU Fengchang1,2,*, GUO Guanghui1,2,3,4, FENG Chenglian1,2 1. State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environment Sciences, Beijing 100012 2. State Environmental Protection Key Laboratory for Lake Pollution Control, Chinese Research Academy of Environment Sciences, Beijing 100012 3. Graduate School of the Chinese Academy of Sciences, Beijing 100049 4. Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640;Comparison of mercury species sensitivity distributions of freshwater biota in China and the United States[J];Acta Scientiae Circumstantiae;2012-05
5 LI Jinlong,QIN Zhenkui,SHI Xiaoli,and ZHANG Zhifeng(Key Laboratory of Marine Genetics and Breeding,Ministry of Education, Ocean University of China,Qingdao 266003,China);ACUTE TOXICITY OF CU~(2+) AND EFFECTS OF ANTIOXIDANT ENZYME ON URECHIS UNICINCTUS BODY WALL[J];Transactions of Oceanology and Limnology;2012-02
6 LUO Dong-mei,SHE Rui-ping,HU Yan-xin,WU Qiong,LIU Tian-long,ZHAI Li-jian1(College of Veterinary Medicine.China Agricultural University,Beijing 100094,P.R.ChinaDepartment3,Command and Engineering College of Chemical Defence of Chinese PLA1,Beijing 102205,P.R.China);Damage of Bisphenol A on Reproductive System and Effects the Expression of Bax and Bcl-2 Genes Induced in Male Rats[J];Science Technology and Engineering;2008-07
7 ZHOU Qi-xing 1 , TENG Yong 1 , LIN Da-song 2 ( 1.Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China; 2.Key Laboratory of Original Environmental Quality, Ministry of Agriculture, Tianjin Key Laboratory of Agro-Environment and Food Safety, Institute of A-gro-environmental Protection, Ministry of Agriculture, Tianjin 300191, China);The Principles and Methods of Deriving and Determining Remediation Criteria for Contaminated Soils[J];Journal of Agro-Environment Science;2013-02
8 MENG Fan-Ping,GAO Ying,ZHAO Shun-Shun,FU Hai-Fang,XIAO Jing(Key of Marine Environment Science and Ecology,Ministry of Education,Ocean University of China,Qingdao 266100,China);Response of Molecular Biomarkers in Bivalves to Heavy Metals in Seawater:A Review[J];Periodical of Ocean University of China;2011-05
9 ZHU Wen-liang(Guangdong testing institute for product quality,Guangzhou,Guangdong510330,China);Progress on contaminants migration from food plastic packing materials[J];Food & Machinery;2010-06
10 DU Yan,DAI Han-hui,WU Yang,ZHANG Li-lan,WU De-yin,WANG Xu-liang(Chinese Academy of Inspection and Quarantine,Beijing 100025);Toxicological characteristic of BPA and opinion of risk-assessment about BPA used as food wrapper in our country and abroad[J];Food Science and Technology;2007-10
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
2 Yi Shaoxuan 1,Li Dacheng 2,Wang Hao 2,Zhau Xiaoliu 2,Fu Jiliang 3 1Dept. of Molecular Biology,Third Military Medical College,Chongqing 630038; 2Dept. of Molecular Biology,West China University of Medical Science; 3Dept. of Biology,Second Milita;THE ESTABLISHMENT OF pS189/FLCⅢ 2 SYSTEM FOR MUTAGENESIS STUDY[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1996-05
3 Hu Bin 2, Cao Jia 2, Cheng Ge 3, Cheng Tian Min 2 1 Department of Health Toxicology and Occupational Health, Sun Yat Sen University of Medical Sciences\ Guang zhou\ 510089\ 2 Department of Preventive Medicine, Third Military Medical University, Chong;STUDY OF THE ANEUPLOID EFFECT OF GLYCIDYL METHACRYLATE (GMA) USING FLUORESCENCE IN SITU HYBRIDIZATION AND CREST STAINING[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1998-02
4 LU Fengmin#, LIU Shuang, WU Weidong, AN Wenfeng, LIU Xiang, LIU Shijie(#Medical Research Center, the Third Hospital, Beijing Medical University, Beijing 100083);USE OF MESSAGER RNA DIFFERENTIAL DISPLAYTO DETECT GENE EXPRESSION VARIATION INDUCED BY Ni_2O_3[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1998-01
5 Yuan Ye et al(Inst.of Occup. Med, Tongji Med. Univ., # 13, Hangkong Rd., Wuhan 430030 China);STUDY ON LYMPHOCYTES' DNA DAMAGES OF BENZENE EXPOSED WORKERS[J];INDUSTRIAL HEALTH AND OCCUPATIONAL OISEASES;1996-02
6 Niu Yujie Department of Occupational Health,the School of Public Health,Hebei Medical University (Shijiazhuang 050017) Shi Nian Li Long Liu Yugu Department of Environmental Toxicology,Tongji Medical University;EFFECT OF PYRETHROIDS ON THE CONTENT OF GLUTAMATE AND ASPARTATE IN RAT BRAIN[J];JOURNAL OF HEBEI MEDICAL UNIVERSITY;1999-01
7 Tang Cuyue, Ma Tangeng, Liu Yugu (Institute of Environmental Toxicology, Tongji University, Wuhan);EFFECTS OF PERMETHRIN AND CYPERMETHRIN ON THE FLUIDITY OF RAT ERYTHRQCYTE GHOST MEMBRANES[J];Acta Scientiae Circumstantiae;1988-04
8 Li Xiuyi;et al.(Norman Bethune University of Medical Sciences,Chang chun,130021);Influence of Low Dose Methylmercury on Cell Cycle Progression of Thymocytes and Splenocytes in Mice[J];JOURNAL OF ENVIRONMENT AND HEALTH;1994-03
9 Li Jingshun,Zhao Shuhua,Jin Minghua,et al.School of Preventive Medicine,Norman Bethune University of Medical Sciences.Changchun 130021;Effect of Methylmercury Chloride on Ovary Cell Cycle in Mice[J];JOURNAL OF ENVIRONMENT AND HEALTH;1997-06
10 Yu Rian,Chen Xuemin Department of Environmental Health,Tongji Medical University,Wuhan 430030;The Effect of Selenium on DNA Damage in Rat Liver Cells[J];JOURNAL OF ENVIRONMENT AND HEALTH;1998-05
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