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《Acta Scientiae Circumstantiae》 1987-02
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RETENTION OF FISSION PRODUCT ~(170)Tm AND ITS MUTAGENIC EFFECT ON BONE MARROW CELLS

Zhu Shoupeng, Zheng Siying, Wang Chongdao, Cao Genfa, Wang Liuyi, Zhao Xiuying (Faculty of Radiological Medicine, Suzhou Medical College, Suzhou)  
After injection of 170Tm with a dose of 1.85×104kBq/kg to male Wistar rats, the radioactivities of tissue samples were determined at different intervals by homogeneous scintillation counting. The retention data were well described by a three exponential expressions. Retentive t1/2, in the rats ranged from 1.25 d for the fast component to 257 d for the slow one. Retention dynamics of 170Tm in the body showed that from very early stage its accumulation in the skeleton began to increase steadily and its radioactivity ranked first in all tissues until the day 91. The study on the chromosome aberration of bone marrow cells indicated that chromosome aberration was of the chromatid type and its rate increased with elevation of absorption dose of 170Tm in the bone.
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【References】
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【Citations】
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【Co-citations】
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1 Zhu Shoupcng; Lun Minyue(Suzhou Medical College,Suzhou 215007);THE METABOLICCHARACTERISTICSOF3H-TdRINORGAN-ISMONINDUCTIONOFREPRODUCTIONTOXICITY[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1996-02
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8 Luo Meichu; Zhang Meizhen; Sun Meizhen; Chen Zhijie(Shanghai Institute of Radiation Medicine ,200032 );STUDIES OF THE COMPETITION FOR THORIUM ION BETWEEN CHELATING AGENTS AND BOVINE SERUM ALBUMIN[J];PADIATION PROTECTION;1995-02
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【Co-references】
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1 Zhu Shoupeng;Zheng Siying;Cao Genfa Faculty of Radiological Medicine, Suzhou Medical College;COMPARING THE MUTAGENIC EFFECT ON BONE MARROW CELLS INDUCED BY DIFFERENT RADIATOR NUCLIDES WITH SIMILAR METABOLIC PECULIARITY[J];Journal of Radiation Research and Radiation Processing;1987-01
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