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《Journal of Environment and Health》 2004-05
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The Assist Protection by Beta,Carotene Against Gamma Radiation

LI Yi,lan, QIAO Shan,shan, ZHOU Lei, et al. Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China  
Objective To study the anti,radiation effect of beta,carotene(β,C). Methods The different doses of β,C (30,60 and 90 mg/kg bw) were orally administered separately to three groups of mice, and a control group was also arranged. The four groups of mice were exposed to 60Co,γ rays after 30 days, then all groups were continuously orally administered, the survival rates, survival time, number of white blood cells(WBC), micronucleus frequency(MF), spermatocyte chromosome abberation, immune function, superoxide dismutase(SOD) activity were measured. Results The results showed that compared with control group, groups treated withβ,C expressed lower range WBC decrease, stronger immune function, higher SOD activity, less MF, longer survival time and improved survival rates. Conclusion β,C had radioprotective effect.
【Fund】: 天津市自然科学基金资助项目(013613011)
【CateGory Index】: R151
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