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《Journal of Environment and Health》 2008-08
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Effect of Cypermethrine on Reproductive Organs of Female Rats

LI Hai-bin LI Jun YAO San-qiao.Occupational and Environmental Health,XinxiangMedical University,Xinxiang,He'nan 453003,China  
Objective To study the effect of cypermethrine (CP) on the reproductive organs of female rats.Methods Fifty female SD rats (90-110 g) were randomly divided into 5 groups,negative control (earthnut oil),three CP treatment groups(20,40 and 80 mg/kg body) and positive control (E_2 100μg/kg body),treated by gavage,once a day,for 28 consecutive days.Results Compared with the negative group,the opening of vagina in different cypermethrine groups were significantly moved up in the first week (P0.05),and the weight and organ coefficient of ovary,uteri and vaginas were significantly increased in cypermethrine groups (P0.05).Conclusion Cypermethrine has a adverse effect on the reproductive organs of female rats.
【CateGory Index】: R114
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