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《Journal of Environment and Health》 2009-03
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Effect of 1800 MHz Electromagnetic Field on Hippocampal P50 Auditory Evoked Potential in Male Rats

LI Hong-ling,ZHOU Hao,LIU Song,et al.College of Public Health,Kunming Medical University,Kunming,Yunnan 650031,China.  
Objective To study the effect of exposure to 1 800 MHz electromagnetic field on the sensory gating P50 of the hippocamp of male rats.Methods Forty-eight male SD rats aged 4 weeks,were randomly divided into four groups,included 2 exposed groups and their respective sham-controls,12 in each group.The rats were exposed to 1 800 MHz microwave fields with power density of 0.5 mW/cm2 or 1.0 mW/cm2,12 h/d,for 21 consecutive days.The sensory gating P50 was recorded by the conditioning-testing paradigm presented with auditory double-clicks stimuli.Results There was significant difference of the peak-peak size of S2,the S2/S1 ratio of the sensory gating P50 in the hippocamp between the exposed groupsⅠand control groups(P 0.05).No significant difference was seen in the S2/S1 ratio,the peak-peak size of S2,the peak-peak size of S1 among the other groups(P0.05).Conclusion Exposure to 1 800 MHz-electromagnetic field,0.5 mW/cm2,may produce an adverse effect on the sensory gating P50 in male rats.
【Fund】: 国家自然科学基金资助项目(30771773)
【CateGory Index】: R594.8
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