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《Journal of Environment and Health》 2009-06
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Air Pollutants-Asthma Triggers and Mechanisms

WANG Qiang, BAI Xue-tao, XU Dong-qun.National Institute for Environmental Health and Related Product Safety,Chinese Center for Disease Control and Prevention, Beijing 100021,China  
Asthma is a chronic respiratory disease with various etiologic factors.Asthma is believed as a result of interaction between gene variation and environmental factors.Asthma increased rapidly worldwide in recent 40 years, air pollutants are believed to be the important triggers, crossover design and multi-pollutant models were used in the further studies.Although some efforts had been made in the mechanism of asthma triggers, they were limited to the lab studies.Studies in asthma related SNP and its interaction with air pollutants will be a revised method in mechanism researches.Based on epidemiological studies, in vivo and in vitro studies, the biological effects and mechanisms of air pollutants on asthma were discussed and evaluated in this paper.
【Fund】: 科技部“十一五”支撑项目(2006BAI19B05)
【CateGory Index】: R562.25
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