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《Journal of Environment and Health》 2009-07
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Genetic Toxicity of Mercury, Cadmium, Lead, Chromium and Arsenic to Vicia faba Root Tip Cells

WU Li-na, SUN Zeng-rong, LU Yan. Department of Environmental Health, School of Public Health,Tianjin Medical University, Tianjin 300070,China  
Objective To evaluate the mutagenicity of mercury, cadmium, arsenic, chromium(Ⅵ)and lead in water on Vicia faba root tip cells. Methods The micronucleus assay of Vicia faba root tip cells were conducted to determine micronucleus rate of Vicia faba root tip cells induced by mercury (0.000 5-1.0 mg/L), cadmium (0.005-1.0 mg/L), arsenic(0.05-2.0 mg/L), chromium (Ⅵ) (0.05-2.0 mg/L) and lead (0.05-3.0 mg/L ) ,and pollution indexes were calculated. Results When the concentration of mercury was ≥ 0.5 mg/L, cadmium ≥ 0.1 mg/L, arsenic ≥ 0.5 mg/L and chromium(Ⅵ)≥ 2.0 mg/L in the water, the micronucleus rate were significantly higher compared with the negative control group, respectively(P0.05, P0.01)and pollution index was 1.5- 2.4. Conclusion When the exposure level through water is higher, mercury, cadmium, arsenic, chromium(Ⅵ)may present genetic toxicity to Vicia faba root tip cells.
【Fund】: 天津市科技攻关计划重大科技工程项目(05ZHGCNC01600)
【CateGory Index】: R114
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