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《Journal of Environment and Health》 2009-08
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Resistibility of Microbes Contaminated in Cosmetics to Preservatives in Common Use in Cosmetics

ZHENG Ping,CHEN Xi-ping.Institute of Environmental Health and Related Product Safety,Chinese Center for Disease Control and Prevention,Beijing 100021,China  
Objective To research the resistibility of microbes contaminated in cosmetics to preservatives in common use in cosmetics.Methods The minimum inhibitory concentration(MIC) method was used according to Disinfection Technical Guideline.Results The resuls showed that some of the isolated microbes had higher resistance for one or more of the commonly used preservatives.The MIC of enterobacter gergoviae for methyl paraben was 10 mg/ml,the MIC of paecilomyces for propyl paraben was 10 mg/ml,it was 2.5 times greater than the limited dose.The MIC of Pantoea,P.luteola and trichoderma for imidazolidinyl urea were higher than other standard microbe strains.Conclusion The microbes contaminated in cosmetics can develop tolerance to the preservatives in common use in cosmetics,maybe that is one of the causes for cosmetics contamination.
【CateGory Index】: TQ658
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