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《Heilongjiang Medicine Journal》 2012-04
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Study on Extraction Process of Coptis Chinensis Franch

Li Mingyue Biological Engineering Co.,Ltd,Harbin Pharmaceutical Group  
Making the contents of the berberine which are from the extracts as the target,HPLC and the orthogonal test use to select the best process for extracting the CCF.The experiment shows that in the condition of using the coarse powder of the CCF and using 12 times of water to extract twice and 1.5 hours each time,it has the similar effect with using the concentration of 70﹪ ethanol.Therefore it is feasible to extract the berberine by water.Making water instead of alcohol as the solvent can not only assure the quality of the extracts but also reduce the cost of the raw and semifinished materials.This study has some value of reference for the industrial production of berberine in the CCF.
【CateGory Index】: TQ461
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