Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of East China University of Science and Technology(Natural Science Edition)》 2009-04
Add to Favorite Get Latest Update

Relationship between LHβ,FSHβ Genes and Central Precocious Puberty in Chinese Girls Based on the Polymorphisms in the 5′-Flanking Regions

ZHAO Ying~1,ZHOU Yu-xun~2,LI Kai~2,XIAO Jun-hua~2(1.School of Bioengineering,East China University of Science and Technology,Shanghai 200237,China;2.Institute of Biology Science and Technology,Donghua University,Shanghai 201620,China)  
In this paper,four single nucleotide polymorphisms(LHβ-1424 C/G,LHβ-238 G/A,FSHβ-261 G/T,FSHβ-132 T/A) in the 5′ upstream regions of LHβ and FSHβ were found in 27 case samples by sequencing.And these four SNPs were genotyped in 283 chinese girls suffered central precocious puberty(CPP) and 284 normal girls.Results show that the association of four polymorphisms in the 5′ upstream regions of LHβ and FSHβ with CPP is not significant(P0.05).And there is no relationship between the CPP and the SNPs in the transcriptional regulation region of LHβ and FSHβ.
【Fund】: 国家自然科学基金(30771191);; 上海市科学基金(071409004)
【CateGory Index】: R725.8
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Li-Xia1, PAN Shi-Yang1, CHEN Dan1, XIE Er-Fu1, GAO Li1, SHU Yong-Qian2, LU Zu-Hong3, CHENG Lu3, YANG Di4, ZHANG Ji-Nan4 1. Center of Clinical Laboratory, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China 2. Department of Oncology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China 3. Department of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, P. R. China 4. Department of Cardiovascular Disease, The First Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China;Effect of Adenomatous Polyposis Coli(APC) Promoter Methylation on Gene Transcription in Lung Cancer Cell Lines[J];Chinese Journal of Cancer;2007-06
2 TENG Li-Juan, LI KeDepartment of Molecular Epidemiology, Medical College, Shantou University, Shantou, Guangdong, 515041, P. R. China;Research Progress on the Relationship between Nutrition and Cancer Epigenetics——Histone Modification Mechanisms[J];Chinese Journal of Cancer;2007-09
3 ZHU Shun-ye1,CHEN Hong-shan2,MA Hua-mei2,LI Yan-hong2,PAN Si-nian1,SU Zhe2,GU Yu-fen2,DU Min-lian2.(1 Department of Pediatrics,the Third Affiliated Hospital of Zhongshan University,Guangzhou,Guangdong 510630,China;2 Department of Pediatrics,the First Affiliated Hospital of Zhongshan University,Guangzhou,Guangdong 510080,China);Growth effect of stanazolol in girls with central idiopathic precocious puberty treated with GnRH analogue.[J];Chinese Journal of Child Health Care;2009-01
4 Zou Qilian~(1),Chen Yuanzhong~(2),Lin Ying~(1),Lin Xiangquan~(3)1.Division of Cell Biology and Genetics,Fujian Medical University,Fuzhou 350004,China2.Fujian Institute of Hematology,The Affiliated Union Hospital,Fujian Medical University,Fuzhou 350001,China3.Fuzhou Children Hospital,Fuzhou 350005,China;Relationship between Genetic Polymorphism of Haptoglobin and Five Polygenetic Inherited Diseases in Children[J];Journal of Fujian Medical University;2006-06
5 Lian Qun.Department of Pediatrics,the First Hospital of Xiamen,Xiamen 361000,China;Impacts of different courses with gonadotropin-releasing hormone agonist on predicted adult height in female children with idiopathic central precocious puberty[J];Fujian Medical Journal;2006-06
6 Zhang Yong,Qin Na,Cao Ji,et al.(Department of Radiotherapy,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021 China);PRELIMINARY STUDIES ON THE METHYLATION OF GENE RUNX3 IN NASOPHARYNGEAL CARCINOMA[J];Journal of Guangxi Medical University;2009-02
7 LIANG Zhen-hua, DAI Yi, HUANG Ying, HUANG Xiao-fangDepartment of Pediatrics,The People's Hospital of Guangxi Zhuang Autonomous Region (Nanning 530021),China;Analysis of leptin level of serum in girls with idiopathic central precocious puberty[J];Guangxi Medical Journal;2005-04
8 Hong-Li Li,1 Wei-Dong Zhang,2 Wen-Tong Li2 and Chong-Gao Yin31.Medicine Research Experiment Center of Science Research, Weifang Medical College, Weifang, Shandong, 261042, P.R.China 2.Department of Pathology, Weifang Medical College, Weifang, Shandong, 261042, P.R.China 3.Department of Nursing, Weifang Medical College, Weifang, Shandong, 261042, P.R.China;Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2[J];Chinese Journal of Cancer;2009-09
9 WU Chun-tai,LI Wei-guo,GAO Xin-sheng,ZHANG Xiao-fei(1.Rubber Research Institute,Chinese Academy of Tropical Agriculture Sciences,Danzhou,Hainan 571737;2.State Center for Rubber Breeding,Danzhou,Hainan 571737;3.Key Laboratory for Tropical Crops Physiology,Ministry of Agriculture,Danzhou,Hainan 571737,China);Methylation-sensitive Amplified Polymorphism and Its Application Prospect in Hereditary and Breeding of Rubber Trees[J];Guizhou Agricultural Sciences;2009-11
10 Wu Junye ,et al Harbin longwei medicine science and technology development Limited company;Molecular Mechanism Analysis of Etiology Pathogenesis and Guiding Radiation Therapy Significance of Nasopharyngeal Carcinoma RUNX3 Genemethylation Changes[J];Heilongjiang Medicine Journal;2009-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved