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《Heilongjiang Medical Journal》 2009-07
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Clinical Observation about Mannitol Preventing TURS in Senile Patients

LI Xiao-dian,ZHOU Ping,HUANG Hui (Department of Anesthesiology,The Ninth People’s Hospital of Chongqing City,Chongqing 400700,China)  
Objective The clinical effect was researched that using 5% mannitol injection as irrigating solution prevent transurethral resection (TURS) in senile patients during the transurethral resection of prostate (TUVP) of benign prostate hyperplasia (BPH) patients. Methods 92 BPH patients,ASA Ⅰ~Ⅲ degree,between 70 and 94 years old in our hospital were fractionated into two random groups. A was experiment group,irrigating solution was 5% mannitol injection. B was control group,irrigating solution was 5% amylaceum injection.Combined spinal-epidural anesthesia or epidural anesthesia was used in the two groups. Venous blood were phlebotomized in order to detect serum natrium(Na+),serum potassium(K+),blood glucose(Glu),haematoglobin (Hb) and Hct in T0,T30 and T60,MAP and Heart Rate was detected during operation. TURS incidence,OP time,irrigating solution dosage and transfusion dosage were recorded. Results It was not significant(P0.05)in MAP、HR、Na+、K+、Glu、Hb、Hct of A group compare to preoperative. However it was significant (P0.05) in MAP、Na+、Hb、Hct of B group in T60,Glu was high in T0 and significant high(P0.01) in T60. In three time points,there were significant deviation(P0.05)about MAP、Hb、Hct in T60 ,there was more significant deviation(P0.01)about Glu in T60.TURS was found in A group,four TURS in B group was 8%. Conclusion 5% mannitol injection as irrigating solution in TUVP can decrease absorption of irrigating solution and decrease TURS incidence in senile patients compared with 5% amylaceum injection.
【CateGory Index】: R699.8;R614
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