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《Henan Journal of Oncology》 1996-03
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Study on Biological Effects of Gynostemma Pentaphyllum Makino Polysaccharide (GPS)

Lou Zhenling; Ma Liping; Zhang Xiaoqin, et al(Department of Esophageal Cancer Studies, Henan Medical University, Zhengzhou 450052)  
Great attention was paid to Gynostemma Pentaphyllun Makino (cucurbitaceae) as containing ginsenoside and having panax effects. By now, the study on the biological effects of the active principle on the Gynostemma Pentaphyllum Makino has not been reported except the Gypenosides. The biological effects of Gynostemma Pentaphyllum Makino Polysaceharide GPS reported here include their antioxidation and immunopotentiation. The experimental results indicated that ①GPS (oral 5mg a day ) could decrease the lipoperoxied of lipied (LPO) level and increase the activity of the superoxide dismutate (SOD) in the normal mice, (P0.05) ②GPS (oral sing a day) could strikingly decrease the LPO level of lipide (P0.01),and obviously increase the SOD activity in subacute senium mice. (P0.01)③ GPS had remarkable cellular immunologic function. The proliferation reaction of splenocytes, the macrophage C3b recepter and macrophage function were significantly improved(p 0.01).
【CateGory Index】: Q53
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